Burkholderia mallei NCTC 10229, BMA10229_0710 (bimA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Burkholderia mallei NCTC 10229
GCF_000015605.1|latest
Locus Tag
BMA10229_0710
NCBI Locus TagBMA10229_RS03035
Name
bimA
Replicon chromosome II
Genomic location 746667 - 747245 (+ strand)

Cross-References

RefSeq YP_001024525.1
GI 124381980
Entrez 4790040
GI 124381980
NCBI Locus Tag BMA10229_RS03035
NCBI Old Locus Tag BMA10229_0710
RefSeq WP_004266230.1
UniProtKB Acc A2RXV6
UniProtKB ID A2RXV6_BURM9

Product

Feature Type CDS
Coding Frame 1
Product Name
Burkholderia intracellular motility A, BimA
Product Name Confidence: Class 2
Synonyms intracellular motility protein A
Evidence for Translation
Charge (pH 7) 3.19
Kyte-Doolittle Hydrophobicity Value -0.163
Molecular Weight (kDa) 19537.5
Isoelectric Point (pI) 9.66

Subcellular localization

Individual Mappings
Localization Confidence PMID
Outer Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database VFDB : VF0427
Category Burkholderia intracellular motility A
Evidence ECO:0000250
sequence similarity evidence used in manual assertion
Host Organism
Notes
Annotation transferred from Burkholderia pseudomallei K96243
Reference 17984080

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 62 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG019364 (221 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BMA10229_0710
Search term: bimA

Human Homologs

References

Identification of a bacterial factor required for actin-based motility of Burkholderia pseudomallei.
Stevens MP, Stevens JM, Jeng RL, Taylor LA, Wood MW, Hawes P, Monaghan P, Welch MD, Galyov EE
Mol Microbiol 2005 Apr;56(1):40-53
PubMed ID: 15773977