Burkholderia cenocepacia K56-2Valvano, BURCENK562V_RS04510 (fliI)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Burkholderia cenocepacia K56-2Valvano
Locus Tag
BURCENK562V_RS04510
NCBI Old Locus TagBURCENK562V_C0718
Name
fliI
Replicon ctg7180000002936
Genomic location 591309 - 592853 (+ strand)

Cross-References

RefSeq WP_020979409.1
GI 537730304
GI 537730304
NCBI Locus Tag BURCENK562V_RS04510
NCBI Old Locus Tag BURCENK562V_C0718
RefSeq WP_020979409.1

Product

Feature Type CDS
Coding Frame 1
Product Name
FliI
Product Name Confidence: Class 1
Evidence for Translation
Charge (pH 7) -6.22
Kyte-Doolittle Hydrophobicity Value 0.027
Molecular Weight (kDa) 54367.4
Isoelectric Point (pI) 6.31

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Virulence Evidence

Source 1
Database BGD
Category Flagella
Evidence ECO:0000315
mutant phenotype evidence used in manual assertion
Host Organism Homo sapiens
Notes fliI mutation in J2315 has reduced invasion of A549 cell monolayers
Reference 11895941

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002892 (678 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: fliI
Search term: FliI

References

Role of flagella in host cell invasion by Burkholderia cepacia.
Tomich M(1), Herfst CA, Golden JW, Mohr CD.
Infect Immun. 2002 Apr;70(4):1799-806.
PubMed ID: 11895941