Burkholderia cenocepacia K56-2Valvano, BURCENK562V_RS17190

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Burkholderia cenocepacia K56-2Valvano
Locus Tag
BURCENK562V_RS17190
NCBI Old Locus TagBURCENK562V_C4999
Name
Replicon ctg7180000002940B
Genomic location 2538949 - 2539449 (- strand)

Cross-References

RefSeq WP_006485048.1
GI 493531043
GI 493531043
NCBI Locus Tag BURCENK562V_RS17190
NCBI Old Locus Tag BURCENK562V_C4999
RefSeq WP_006485048.1

Product

Feature Type CDS
Coding Frame 1
Product Name
Cro/Cl family transcriptional regulator
Product Name Confidence: Class 1
Evidence for Translation
Charge (pH 7) -1.02
Kyte-Doolittle Hydrophobicity Value 0.234
Molecular Weight (kDa) 17047.5
Isoelectric Point (pI) 5.08

Subcellular localization

Individual Mappings
Localization Confidence PMID
Fimbrial
Note: This is based on PSORTb V3.0 secondary localization prediction
Class 3
Extracellular Class 3
Additional evidence for subcellular localization

Virulence Evidence

Source 1
Database BGD
Category Cable pili
Evidence ECO:0000315
mutant phenotype evidence used in manual assertion
Host Organism Homo sapiens
Notes Cable pili are necessary for inducing A549 transformed human epithelial lung cell death via apoptosis
Reference 17537663

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG005919 (93 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:

References

Pilus-mediated epithelial cell death in response to infection with Burkholderia cenocepacia.
Cheung KJ Jr(1), Li G, Urban TA, Goldberg JB, Griffith A, Lu F, Burns JL.
Microbes Infect. 2007 Jun;9(7):829-37.
PubMed ID: 17537663