Burkholderia cenocepacia K56-2Valvano, BURCENK562V_RS23390 (pvdA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Burkholderia cenocepacia K56-2Valvano
Locus Tag
BURCENK562V_RS23390
NCBI Old Locus TagBURCENK562V_C1526
Name
pvdA
Replicon ctg7180000002938
Genomic location 243158 - 244534 (- strand)

Cross-References

RefSeq WP_006486049.1
GI 493532064
EC Number 1.13.12.-
GI 493532064
NCBI Locus Tag BURCENK562V_RS23390
NCBI Old Locus Tag BURCENK562V_C1526
RefSeq WP_006486049.1

Product

Feature Type CDS
Coding Frame 1
Product Name
L-ornithine 5-monooxygenase
Product Name Confidence: Class 1
Evidence for Translation
Charge (pH 7) -3.52
Kyte-Doolittle Hydrophobicity Value -0.205
Molecular Weight (kDa) 50999.1
Isoelectric Point (pI) 6.57

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Virulence Evidence

Source 1
Database BGD
Category Siderophore biosynthesis and uptake (ornibactin)
Evidence ECO:0000315
mutant phenotype evidence used in manual assertion
Host Organism Rattus norvegicus
Notes BURCENK562V_RS23390 mutant is attenuated for virulence in rat chronic respiratory infection model
Reference 10456885

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG001462 (642 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: pvdA

References

Role of ornibactin biosynthesis in the virulence of Burkholderia cepacia: characterization of pvdA, the gene encoding L-ornithine N(5)-oxygenase.
Sokol PA(1), Darling P, Woods DE, Mahenthiralingam E, Kooi C.
Infect Immun. 1999 Sep;67(9):4443-55.
PubMed ID: 10456885