Burkholderia cenocepacia J2315, BCAM2176 (glsA)

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAM2176
NCBI Locus Tag	QU43_RS65245
Name	glsA
Replicon	chromosome 2
Genomic location	2433646 - 2434560 (+ strand)

Cross-References

RefSeq	WP_006483161.1
GI	206564013
Entrez	6929766
GI	206564013
INSDC	CAR56034.1
NCBI Locus Tag	QU43_RS65245
NCBI Old Locus Tag	BCAM2176
RefSeq	WP_006483161.1,GeneID
UniParc	UPI00017BA148
UniProtKB Acc	B4EFX3
UniProtKB ID	B4EFX3_BURCJ
UniRef100	UniRef100_B4EFX3
UniRef50	UniRef50_A0KNV3
UniRef90	UniRef90_B4EFX3

Product

Feature Type	CDS
Coding Frame	1
Product Name	glutaminase
Synonyms
Evidence for Translation
Charge (pH 7)	-6.25
Kyte-Doolittle Hydrophobicity Value	0.133
Molecular Weight (kDa)	32791.2
Isoelectric Point (pI)	5.00

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 202 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG003917 (642 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAM2176 Search term: glsA Search term: glutaminase

Human Homologs

Ensembl 97, assembly GRCh38.p12	ENSP00000317379 glutaminase [Source:HGNC Symbol;Acc:HGNC:4331] E-value: 7.9e-49 Percent Identity: 37.5
Ensembl 97, assembly GRCh38.p12	ENSP00000340689 glutaminase [Source:HGNC Symbol;Acc:HGNC:4331] E-value: 7.9e-49 Percent Identity: 37.5

References