Burkholderia cenocepacia J2315, BCAL3530 (hupA)

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAL3530
NCBI Locus Tag	QU43_RS54385
Name	hupA
Replicon	chromosome 1
Genomic location	3867242 - 3867520 (- strand)

Cross-References

RefSeq	WP_006401505.1
GI	206561866
Entrez	6933264
GI	206561866
INSDC	CAR53853.1
NCBI Locus Tag	QU43_RS54385
NCBI Old Locus Tag	BCAL3530
RefSeq	WP_006401505.1,GeneID
UniParc	UPI0000274BB9
UniProtKB Acc	B4E7A4
UniProtKB ID	B4E7A4_BURCJ
UniRef100	UniRef100_A0A095GYF1
UniRef50	UniRef50_Q7WX14
UniRef90	UniRef90_B2JJN7

Product

Feature Type	CDS
Coding Frame	1
Product Name	DNA-binding protein HU-alpha
Synonyms
Evidence for Translation
Charge (pH 7)	8.98
Kyte-Doolittle Hydrophobicity Value	-0.358
Molecular Weight (kDa)	9605.0
Isoelectric Point (pI)	10.99

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession	Header	Accession Date	Compound	Source	Resolution	Method	Percent Identity
6N2L	DNA BINDING PROTEIN	11/13/18	Crystal structure of a histone family protein DNA-binding protein from Burkholderia ambifaria	BURKHOLDERIA AMBIFARIA (STRAIN MC40-6)	1.85	X-RAY DIFFRACTION	100.0

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 568 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG000052 (653 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAL3530 Search term: hupA Search term: DNA-binding protein HU-alpha

Human Homologs

References