Burkholderia cenocepacia J2315, BCAL2762 (adk)

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAL2762
NCBI Locus Tag	QU43_RS50425
Name	adk
Replicon	chromosome 1
Genomic location	3033278 - 3033940 (+ strand)

Cross-References

RefSeq	WP_006482212.1
GI	206561099
Entrez	6933773
GI	206561099
INSDC	CAR53062.1
NCBI Locus Tag	QU43_RS50425
NCBI Old Locus Tag	BCAL2762
RefSeq	WP_006482212.1,GeneID
UniParc	UPI000052DE02
UniProtKB Acc	B4E9G1
UniProtKB ID	KAD_BURCJ
UniRef100	UniRef100_Q1BU66
UniRef50	UniRef50_C5BD16
UniRef90	UniRef90_Q2T0K4

Product

Feature Type	CDS
Coding Frame	1
Product Name	adenylate kinase
Synonyms
Evidence for Translation
Charge (pH 7)	-1.31
Kyte-Doolittle Hydrophobicity Value	-0.438
Molecular Weight (kDa)	24237.5
Isoelectric Point (pI)	6.30

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession	Header	Accession Date	Compound	Source	Resolution	Method	Percent Identity
3GMT	TRANSFERASE	03/15/09	Crystal structure of adenylate kinase from burkholderia pseudomallei	BURKHOLDERIA PSEUDOMALLEI 1710B	2.1	X-RAY DIFFRACTION	93.8

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 631 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG002411 (654 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAL2762 Search term: adk Search term: adenylate kinase

Human Homologs

Ensembl 97, assembly GRCh38.p12	ENSP00000362548 adenylate kinase 2 [Source:HGNC Symbol;Acc:HGNC:362] E-value: 6.7e-50 Percent Identity: 49.0
Ensembl 97, assembly GRCh38.p12	ENSP00000447082 adenylate kinase 2 [Source:HGNC Symbol;Acc:HGNC:362] E-value: 6.7e-50 Percent Identity: 49.0
Ensembl 97, assembly GRCh38.p12	ENSP00000346921 adenylate kinase 2 [Source:HGNC Symbol;Acc:HGNC:362] E-value: 6.7e-50 Percent Identity: 49.0

References