Burkholderia cenocepacia J2315, BCAL2676 (pepA)

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAL2676
NCBI Locus Tag	QU43_RS49990
Name	pepA
Replicon	chromosome 1
Genomic location	2943337 - 2944848 (- strand)

Cross-References

RefSeq	WP_006484797.1
GI	206561014
Entrez	6932711
GI	206561014
INSDC	CAR52977.1
NCBI Locus Tag	QU43_RS49990
NCBI Old Locus Tag	BCAL2676
RefSeq	WP_006484797.1,GeneID
UniParc	UPI00017B9771
UniProtKB Acc	B4E8G9
UniProtKB ID	AMPA_BURCJ
UniRef100	UniRef100_B4E8G9
UniRef50	UniRef50_Q8XWQ8
UniRef90	UniRef90_Q2T0C0

Product

Feature Type	CDS
Coding Frame	1
Product Name	leucyl aminopeptidase
Synonyms
Evidence for Translation
Charge (pH 7)	2.97
Kyte-Doolittle Hydrophobicity Value	0.062
Molecular Weight (kDa)	52973.5
Isoelectric Point (pI)	7.98

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 453 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG002337 (652 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAL2676 Search term: pepA Search term: leucyl aminopeptidase

Human Homologs

Ensembl 97, assembly GRCh38.p12	ENSP00000481000 leucine aminopeptidase 3 [Source:HGNC Symbol;Acc:HGNC:18449] E-value: 5.4e-71 Percent Identity: 38.4
Ensembl 97, assembly GRCh38.p12	ENSP00000226299 leucine aminopeptidase 3 [Source:HGNC Symbol;Acc:HGNC:18449] E-value: 5.4e-71 Percent Identity: 38.4
Ensembl 97, assembly GRCh38.p12	ENSP00000476028 leucine aminopeptidase 3 [Source:HGNC Symbol;Acc:HGNC:18449] E-value: 5.4e-71 Percent Identity: 38.4

References