Burkholderia cenocepacia J2315, BCAL1908 (lipA)

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAL1908
NCBI Locus Tag	QU43_RS46085
Name	lipA
Replicon	chromosome 1
Genomic location	2106144 - 2107109 (- strand)

Cross-References

RefSeq	WP_006485081.1
GI	206560272
Entrez	6932111
GI	206560272
INSDC	CAR52209.1
NCBI Locus Tag	QU43_RS46085
NCBI Old Locus Tag	BCAL1908
RefSeq	WP_006485081.1,GeneID
UniParc	UPI00017B91D9
UniProtKB Acc	B4EAZ4
UniProtKB ID	B4EAZ4_BURCJ
UniRef100	UniRef100_B4EAZ4
UniRef50	UniRef50_Q31F42
UniRef90	UniRef90_B4EAZ4

Product

Feature Type	CDS
Coding Frame	1
Product Name	lipoyl synthase
Synonyms
Evidence for Translation
Charge (pH 7)	-0.80
Kyte-Doolittle Hydrophobicity Value	-0.040
Molecular Weight (kDa)	34513.0
Isoelectric Point (pI)	6.85

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 495 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG001673 (232 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAL1908 Search term: lipA Search term: lipoyl synthase

Human Homologs

Ensembl 97, assembly GRCh38.p12

ENSP00000492260 lipoic acid synthetase [Source:HGNC Symbol;Acc:HGNC:16429] E-value: 8.8e-67 Percent Identity: 47.2

References