Burkholderia cenocepacia J2315, BCAL1447 (galU)

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAL1447
NCBI Locus Tag	QU43_RS43740
Name	galU
Replicon	chromosome 1
Genomic location	1598154 - 1599038 (- strand)

Cross-References

RefSeq	WP_006490437.1
GI	206559814
Entrez	6931744
GI	206559814
INSDC	CAR51746.1
NCBI Locus Tag	QU43_RS43740
NCBI Old Locus Tag	BCAL1447
RefSeq	WP_006490437.1,GeneID
UniParc	UPI00017B933E
UniProtKB Acc	B4E713
UniProtKB ID	B4E713_BURCJ
UniRef100	UniRef100_B4E713
UniRef50	UniRef50_Q2SVA0
UniRef90	UniRef90_Q2SVA0

Product

Feature Type	CDS
Coding Frame	1
Product Name	UTP--glucose-1-phosphate uridylyltransferase
Synonyms
Evidence for Translation
Charge (pH 7)	-7.40
Kyte-Doolittle Hydrophobicity Value	-0.081
Molecular Weight (kDa)	32347.0
Isoelectric Point (pI)	5.27

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession	Header	Accession Date	Compound	Source	Resolution	Method	Percent Identity
5VE7	TRANSFERASE	04/04/17	Crystal structure of UTP-glucose-1-phosphate uridylyltransferase from Burkholderia ambifaria in complex with UTP	BURKHOLDERIA AMBIFARIA (STRAIN MC40-6)	2.3	X-RAY DIFFRACTION	96.9
5VCT	TRANSFERASE	03/31/17	Crystal structure of UTP-glucose-1-phosphate uridylyltransferase from Burkholderia ambifaria	BURKHOLDERIA AMBIFARIA (STRAIN MC40-6)	1.9	X-RAY DIFFRACTION	96.9
5J49	TRANSFERASE	03/31/16	Crystal structure of UDP-glucose pyrophosporylase / UTP-glucose-1-phosphate uridylyltransferase from Burkholderia xenovorans	BURKHOLDERIA XENOVORANS (STRAIN LB400)	1.8	X-RAY DIFFRACTION	91.6

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 619 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG001267 (656 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAL1447 Search term: galU Search term: UTP--glucose-1-phosphate uridylyltransferase

Human Homologs

References