Burkholderia cenocepacia J2315, BCAL1439 (msdA)

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAL1439
NCBI Locus Tag	QU43_RS43700
Name	msdA
Replicon	chromosome 1
Genomic location	1589092 - 1590612 (- strand)

Cross-References

RefSeq	WP_006488924.1
GI	206559806
Entrez	6931737
GI	206559806
INSDC	CAR51738.1
NCBI Locus Tag	QU43_RS43700
NCBI Old Locus Tag	BCAL1439
RefSeq	WP_006488924.1,GeneID
UniParc	UPI00017B9337
UniProtKB Acc	B4E705
UniProtKB ID	B4E705_BURCJ
UniRef100	UniRef100_B4E705
UniRef50	UniRef50_Q92RW4
UniRef90	UniRef90_A0A095EDQ0

Product

Feature Type	CDS
Coding Frame	1
Product Name	methylmalonic acid semialdehyde dehydrogenase
Synonyms
Evidence for Translation
Charge (pH 7)	-3.76
Kyte-Doolittle Hydrophobicity Value	0.068
Molecular Weight (kDa)	54030.5
Isoelectric Point (pI)	6.36

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 601 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG001260 (654 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAL1439 Search term: msdA Search term: methylmalonic acid semialdehyde dehydrogenase

Human Homologs

Ensembl 97, assembly GRCh38.p12

ENSP00000450436 aldehyde dehydrogenase 6 family member A1 [Source:HGNC Symbol;Acc:HGNC:7179] E-value: 3.7e-120 Percent Identity: 43.4

References