Log of Annotation Updates

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Date Locus Tag Strain Description Submitter
Apr 10, 2015 BMA10247_A0765 Burkholderia mallei NCTC 10247 New product name: Chaperone protein BicP. New gene name synonym: sicP. New product name confidence: Class 2. New PubMed ID: 20951592. New PubMed ID: 21801239. Annotation transferred from: UniProtKB:P0CL16. Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 10, 2015 BMA10229_2084 Burkholderia mallei NCTC 10229 New product name: Chaperone protein BicP. New gene name synonym: sicP. New product name confidence: Class 2. New PubMed ID: 20951592. New PubMed ID: 21801239. Annotation transferred from: UniProtKB:P0CL16. Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 10, 2015 BMAA1520 New product name: Chaperone protein BicP. New gene name synonym: sicP. New product name confidence: Class 2. New PubMed ID: 20951592. New PubMed ID: 21801239. Annotation transferred from: UniProtKB:P0CL16. Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 10, 2015 BPSS1523 Burkholderia pseudomallei K96243 New product name: Chaperone protein BicP. New gene name synonym: sicP. New PubMed ID: 20951592. New PubMed ID: 21801239. Annotation transferred from: UniProtKB:P0CL16. Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BMAA1541 Burkholderia mallei ATCC 23344 New product name: chaperone protein BsaR (T3SS-3). New product name confidence: Class 2. New PubMed ID: 28664152. New PubMed ID: 16164564. New PubMed ID: 14645290. New comment: This gene is part of the Burkholderia mallei type III secretion system T3SS-3 gene locus..Annotation transferred from: BGD:BPSS1542. Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BPSS1542 Burkholderia pseudomallei K96243 New product name: chaperone protein BsaR (T3SS-3). New product name confidence: Class 2. New PubMed ID: 28664152. New PubMed ID: 16164564. New PubMed ID: 14645290. New comment: This gene is part of the type III secretion system T3SS-3 (bsa) gene locus. BsaR is homologous to the Salmonella chaperone InvB which has been shown to be required for secretion of the effector proteins SopE and SopA (PMID:14645290). BsaR has been predicted to be the chaperone for BopE using a computational screen for chaperones in B. pseudomallei K96243 (PMID:16164564) but this has not been validated yet. Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Jan 14, 2010 BCAL2021 Burkholderia cenocepacia J2315 New product name: Class A penicillin-binding protein. New product name confidence: Class 1. New evidence reference (PMID): 19924480. Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Jan 14, 2010 BCAL0274 Burkholderia cenocepacia J2315 New product name: Class A penicillin-binding protein. New product name confidence: Class 1. New evidence reference (PMID): 19924480. Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Jan 14, 2010 BCAM2632 Burkholderia cenocepacia J2315 New product name: Class A penicillin-binding protein. New product name confidence: Class 1. New evidence reference (PMID): 19924480. Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 20, 2020 BCAM0224 Burkholderia cenocepacia J2315 New product name: collagen type 1-binding trimeric autotransporter adhesin. New product name confidence: Class 1. New comment: BCAM0224 is a trimeric autotransporter adhesin required for cell adhesion and virulence (PMID:20019083). New PMIDs: 22919579, 20019083. Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BPSS1512 Burkholderia pseudomallei K96243 New product name: deubiquitinase TssM. New subcellular localization: Extracellular (Class 1). New subcellular localization evidence code (ECO): ECO:0000112. New subcellular localization PMID: 24866793. New PubMed ID: 19168747. New PubMed ID: 24866793. New comment: Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Jan 25, 2011 BCAL2409 Burkholderia cenocepacia J2315 New product name: DnaE. New pathway: Lipopolysaccharide biosynthesis. New pathway: lipopolysaccharide core region biosynthesis. New GO accession: GO:0009244 [IGC]. New evidence reference (PMID): 19525227. Literature review. Geoffrey L. Winsor (Brinkman Lab). Simon Fraser University, Canada
Apr 30, 2018 BTH_I1476 Burkholderia thailandensis E264 ATCC 700388 New product name: dTDP-Rha 4-epimerase. New PubMed ID: 21640586. Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Aug 1, 2008 Bcen2424_4993 New product name: Fe(III)-pyochelin outer membrane receptor precursor. New product name confidence: Class 2. New homology: 60% identity to Fe[III]-pyochelin outer membrane receptor precursor [P. aeruginosa PAO1]. New evidence reference (PMID): 17295049. New evidence reference (PMID): 8288523. Literature review. Thomas, M. S. University of Sheffield, Sheffield, UK
Aug 1, 2008 Bcen_3374 New product name: Fe(III)-pyochelin outer membrane receptor precursor. New product name confidence: Class 2. New homology: 60% identity to Fe[III]-pyochelin outer membrane receptor precursor [P. aeruginosa PAO1]. New evidence reference (PMID): 17295049. New evidence reference (PMID): 8288523. Literature review. Thomas, M. S. University of Sheffield, Sheffield, UK
Aug 1, 2008 Bcep18194_B0677 New product name: Fe(III)-pyochelin outer membrane receptor precursor. New product name confidence: Class 2. New homology: 60% identity to Fe[III]-pyochelin outer membrane receptor precursor [P. aeruginosa PAO1]. New evidence reference (PMID): 17295049. New evidence reference (PMID): 8288523. Literature review. Thomas, M. S. University of Sheffield, Sheffield, UK
Jan 14, 2010 Bxe_A2876 Burkholderia xenovorans LB400 New product name: Fe2+-dependent oxygenase. New product name confidence: Class 2. New evidence reference (PMID): 19754880. Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 22, 2009 BCAL3378 Burkholderia cenocepacia J2315 New product name: ferric uptake regulator Fur. New product name confidence: Class 2. New evidence reference (PMID): 18057135. Literature review. Dennis, J. J. Department of Biological Sciences, University of Alberta, Edmonton, Alberta.
Apr 30, 2018 BMAA1523 Burkholderia mallei ATCC 23344 New product name: guanine nucleotide exchange factor BopE (T3SS-3). New product name confidence: Class 2. New PubMed ID: 18052936. New PubMed ID: 18654761. New PubMed ID: 24626296. New PubMed ID: 17041850. New PubMed ID: 25635268. New PubMed ID: 28664152. New comment: This gene is part of the Burkholderia mallei type III secretion system T3SS-3 gene locus..Annotation transferred from: BGD:BPSS1525. Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BPSS1525 Burkholderia pseudomallei K96243 New product name: guanine nucleotide exchange factor BopE (T3SS-3). New PubMed ID: 18052936. New PubMed ID: 18654761. New PubMed ID: 24626296. New PubMed ID: 17041850. New PubMed ID: 25635268. New PubMed ID: 28664152. New comment: This gene is part of the type III secretion system T3SS-3 (bsa) gene locus. Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BCAL3112 Burkholderia cenocepacia J2315 New product name: heptosyltransferase I WaaC. New PubMed ID: 19525227. New comment: Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BCAL0967 Burkholderia cenocepacia J2315 New product name: heptosyltransferase II WaaF. New PubMed ID: 19525227. New comment: Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 10, 2015 BCAL2829 Burkholderia cenocepacia J2315 New product name: HtrA protease. Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 10, 2015 BCAL1699 Burkholderia cenocepacia J2315 New product name: L-ornithine 5-monooxygenase. Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Jan 29, 2010 BCAL1699 Burkholderia cenocepacia J2315 New product name: L-ornithine N(5)-oxygenase. New product name confidence: Class 1. New evidence reference (PMID): 10456885. Pamela A. Sokol, University of Calgary
Aug 1, 2008 Bcen2424_1643 New product name: L-ornithine N5-oxygenase. New product name confidence: Class 2. New homology: 51% identity to L-ornithine N5-oxygenase, PvdA[P. aeruginosa PAO1]. New evidence reference (PMID): 17295049. Literature review. Thomas, M. S. University of Sheffield, Sheffield, UK
Aug 1, 2008 Bcen_1163 New product name: L-ornithine N5-oxygenase. New product name confidence: Class 2. New homology: 51% identity to L-ornithine N5-oxygenase, PvdA[P. aeruginosa PAO1]. New evidence reference (PMID): 17295049. Literature review. Thomas, M. S. University of Sheffield, Sheffield, UK
Aug 1, 2008 Bamb_1540 New product name: L-ornithine N5-oxygenase. New product name confidence: Class 2. New homology: 51% identity to L-ornithine N5-oxygenase, PvdA[P. aeruginosa PAO1]. New evidence reference (PMID): 17295049. Literature review. Thomas, M. S. University of Sheffield, Sheffield, UK
Aug 1, 2008 Bcep18194_A4789 New product name: L-ornithine N5-oxygenase. New product name confidence: Class 2. New homology: 51% identity to L-ornithine N5-oxygenase, PvdA[P. aeruginosa PAO1]. New evidence reference (PMID): 17295049. Literature review. Thomas, M. S. University of Sheffield, Sheffield, UK
Apr 10, 2015 BCAM1867 Burkholderia cenocepacia J2315 New product name: MgtC. Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Jan 25, 2011 BCAL2408 Burkholderia cenocepacia J2315 New product name: MsbA. New pathway: Lipopolysaccharide biosynthesis. New pathway: lipopolysaccharide core region biosynthesis. New GO accession: GO:0009244 [IGC]. New evidence reference (PMID): 19525227. Literature review. Geoffrey L. Winsor (Brinkman Lab). Simon Fraser University, Canada
Apr 30, 2018 BMAA1538 Burkholderia mallei ATCC 23344 New product name: needle length control protein BsaU (T3SS-3). New gene name synonym: sctP. New product name confidence: Class 2. New PubMed ID: 28664152. New PubMed ID: 10944190. New PubMed ID: 16714590. New comment: This gene is part of the Burkholderia mallei type III secretion system T3SS-3 gene locus..Annotation transferred from: BGD:BPSS1539. Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BPSS1539 Burkholderia pseudomallei K96243 New product name: needle length control protein BsaU (T3SS-3). New gene name synonym: sctP. New PubMed ID: 28664152. New PubMed ID: 10944190. New PubMed ID: 16714590. New comment: This gene is part of the type III secretion system T3SS-3 (bsa) gene locus. BsaU is homologous to InvJ from Salmonella which is the molecular ruler which determines the length of the T3SS needle. (PMID: 10944190). Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Jan 14, 2010 Bth_I1158 Burkholderia thailandensis E264 ATCC 700388 New product name: Nucleoside kinase. New product name confidence: Class 2. New evidence reference (PMID): 19021762. Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Aug 1, 2008 Bamb_1536 New product name: ornibactin biosynthesis ABC transport protein, OrbE. New product name confidence: Class 3. New homology: 95% identity to ornibactin biosynthesis ABC transport protein, OrbE[B. cenocepacia J2315]. New evidence reference (PMID): 17295049. Literature review. Thomas, M. S. University of Sheffield, Sheffield, UK
Aug 1, 2008 Bcep18194_A4785 New product name: ornibactin biosynthesis ABC transport protein, OrbE. New product name confidence: Class 3. New homology: 97% identity to ornibactin biosynthesis ABC transport protein, OrbE[B. cenocepacia J2315]. New evidence reference (PMID): 17295049. Literature review. Thomas, M. S. University of Sheffield, Sheffield, UK
Aug 1, 2008 Bcen2424_1639 New product name: ornibactin biosynthesis ABC transport protein, OrbE. New product name confidence: Class 3. New homology: 98% identity to ornibactin biosynthesis ABC transport protein, OrbE[B. cenocepacia J2315]. New evidence reference (PMID): 17295049. Literature review. Thomas, M. S. University of Sheffield, Sheffield, UK
Aug 1, 2008 Bcen_1159 New product name: ornibactin biosynthesis ABC transport protein, OrbE. New product name confidence: Class 3. New homology: 98% identity to ornibactin biosynthesis ABC transport protein, OrbE[B. cenocepacia J2315]. New evidence reference (PMID): 17295049. Literature review. Thomas, M. S. University of Sheffield, Sheffield, UK
Aug 1, 2008 Bamb_1537 New product name: ornibactin biosynthesis non-ribosomal peptide, OrbI. New product name confidence: Class 3. New homology: 91% identity to ornibactin biosynthesis non-ribosomal peptide, OrbI[B. cenocepacia J2315]. New evidence reference (PMID): 17295049. New evidence reference (PMID): 16672617. Literature review. Thomas, M. S. University of Sheffield, Sheffield, UK
Aug 1, 2008 Bcep18194_A4786 New product name: ornibactin biosynthesis non-ribosomal peptide, OrbI. New product name confidence: Class 3. New homology: 93% identity to ornibactin biosynthesis non-ribosomal peptide, OrbI[B. cenocepacia J2315]. New evidence reference (PMID): 17295049. New evidence reference (PMID): 16672617. Literature review. Thomas, M. S. University of Sheffield, Sheffield, UK
Aug 1, 2008 Bcen2424_1640 New product name: ornibactin biosynthesis non-ribosomal peptide, OrbI. New product name confidence: Class 3. New homology: 96% identity to ornibactin biosynthesis non-ribosomal peptide, OrbI[B. cenocepacia J2315]. New evidence reference (PMID): 17295049. New evidence reference (PMID): 16672617. Literature review. Thomas, M. S. University of Sheffield, Sheffield, UK
Aug 1, 2008 Bcen_1160 New product name: ornibactin biosynthesis non-ribosomal peptide, OrbI. New product name confidence: Class 3. New homology: 96% identity to ornibactin biosynthesis non-ribosomal peptide, OrbI[B. cenocepacia J2315]. New evidence reference (PMID): 17295049. New evidence reference (PMID): 16672617. Literature review. Thomas, M. S. University of Sheffield, Sheffield, UK
Aug 1, 2008 Bamb_1538 New product name: ornibactin biosynthesis non-ribosomal peptide, OrbJ. New product name confidence: Class 3. New homology: 91% identity to ornibactin biosynthesis non-ribosomal peptid, OrbJ[B. cenocepacia J2315]. New evidence reference (PMID): 17295049. New evidence reference (PMID): 16672617. Literature review. Thomas, M. S. University of Sheffield, Sheffield, UK
Aug 1, 2008 Bcep18194_A4787 New product name: ornibactin biosynthesis non-ribosomal peptide, OrbJ. New product name confidence: Class 3. New homology: 92% identity to ornibactin biosynthesis non-ribosomal peptid, OrbJ[B. cenocepacia J2315]. New evidence reference (PMID): 17295049. New evidence reference (PMID): 16672617. Literature review. Thomas, M. S. University of Sheffield, Sheffield, UK
Aug 1, 2008 Bcen2424_1641 New product name: ornibactin biosynthesis non-ribosomal peptide, OrbJ. New product name confidence: Class 3. New homology: 95% identity to ornibactin biosynthesis non-ribosomal peptid, OrbJ[B. cenocepacia J2315]. New evidence reference (PMID): 17295049. New evidence reference (PMID): 16672617. Literature review. Thomas, M. S. University of Sheffield, Sheffield, UK
Aug 1, 2008 Bcen_1161 New product name: ornibactin biosynthesis non-ribosomal peptide, OrbJ. New product name confidence: Class 3. New homology: 95% identity to ornibactin biosynthesis non-ribosomal peptid, OrbJ[B. cenocepacia J2315]. New evidence reference (PMID): 17295049. New evidence reference (PMID): 16672617. Literature review. Thomas, M. S. University of Sheffield, Sheffield, UK
Aug 1, 2008 Bamb_1539 New product name: ornibactin biosynthesis protein, OrbK. New product name confidence: Class 3. New homology: 86% identity to ornibactin biosynthesis protein, OrbK[B. cenocepacia J2315]. New evidence reference (PMID): 17295049. Literature review. Thomas, M. S. University of Sheffield, Sheffield, UK
Aug 1, 2008 Bcep18194_A4788 New product name: ornibactin biosynthesis protein, OrbK. New product name confidence: Class 3. New homology: 90% identity to ornibactin biosynthesis protein, OrbK[B. cenocepacia J2315]. New evidence reference (PMID): 17295049. Literature review. Thomas, M. S. University of Sheffield, Sheffield, UK
Aug 1, 2008 Bcen2424_1642 New product name: ornibactin biosynthesis protein, OrbK. New product name confidence: Class 3. New homology: 94% identity to ornibactin biosynthesis protein, OrbK[B. cenocepacia J2315]. New evidence reference (PMID): 17295049. Literature review. Thomas, M. S. University of Sheffield, Sheffield, UK
Aug 1, 2008 Bcen_1162 New product name: ornibactin biosynthesis protein, OrbK. New product name confidence: Class 3. New homology: 94% identity to ornibactin biosynthesis protein, OrbK[B. cenocepacia J2315]. New evidence reference (PMID): 17295049. Literature review. Thomas, M. S. University of Sheffield, Sheffield, UK
Aug 1, 2008 Bcep18194_A4790 New product name: ornibactin receptor precursor, OrbA. New product name confidence: Class 2. New subcellular localization confidence: Class 2. New homology: 91% identity to ornibactin receptor precursor [B. cenocepacia K56-2]. New evidence reference (PMID): 17295049. New evidence reference (PMID): 11083764. Literature review. Thomas, M. S. University of Sheffield, Sheffield, UK
Aug 1, 2008 Bcen2424_1644 New product name: ornibactin receptor precursor, OrbA. New product name confidence: Class 2. New subcellular localization confidence: Class 2. New homology: 94% identity to ornibactin receptor precursor [B. cenocepacia K56-2]. New evidence reference (PMID): 17295049. New evidence reference (PMID): 11083764. Literature review. Thomas, M. S. University of Sheffield, Sheffield, UK
Aug 1, 2008 Bcen_1164 New product name: ornibactin receptor precursor, OrbA. New product name confidence: Class 2. New subcellular localization confidence: Class 2. New homology: 94% identity to ornibactin receptor precursor [B. cenocepacia K56-2]. New evidence reference (PMID): 17295049. New evidence reference (PMID): 11083764. Literature review. Thomas, M. S. University of Sheffield, Sheffield, UK
Apr 10, 2015 BMA10247_A0732 Burkholderia mallei NCTC 10247 New product name: Oxygen-regulated invasion protein OrgA. New product name confidence: Class 2. New PubMed ID: 20951592. Annotation transferred from: UniProtKB:E1WAB5. Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 10, 2015 BMA10229_2053 Burkholderia mallei NCTC 10229 New product name: Oxygen-regulated invasion protein OrgA. New product name confidence: Class 2. New PubMed ID: 20951592. Annotation transferred from: UniProtKB:E1WAB5. Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 10, 2015 BMAA1551 New product name: Oxygen-regulated invasion protein OrgA. New product name confidence: Class 2. New PubMed ID: 20951592. Annotation transferred from: UniProtKB:E1WAB5. Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 22, 2009 BCAM0857 Burkholderia cenocepacia J2315 New product name: phosphotyrosine phosphatase BceD. New product name confidence: Class 1. New homology: 90% identity to BceD[ B. cepacia IST408]. New evidence reference (PMID): 17114319. Literature review. Raymond C. Lo, Simon Fraser University
Apr 10, 2015 BCAM0267 Burkholderia cenocepacia J2315 New product name: porin. New product name confidence: Class 1. New PubMed ID: 14977960. Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BCAL3125 New product name: pseudogene (WbxB). New product name confidence: Class 2. New PubMed ID: 15687196. New comment: Belongs to the O antigen biosynthesis gene cluster. New comment: B cenocepacia J2315, but not K56-2, is O-antigen deficient due to a transposon insertion in this gene. Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 WQ49_RS09445 Burkholderia cenocepacia K56-2 New product name: putative (R)-specific oxepin-CoA hydratase. New product name synonym: PaaZ-ECH. New product name confidence: Class 2. New PubMed ID: 21296885. New comment: in E coli, paaZ encodes a bifunctional protein consisting of an N-terminal NADP-dependent aldehyde dehydrogenase domain and a C-terminal MaoC-like (R)-specific enoyl-CoA hydratase domain. In Burkholderia genomes, a gene incorrectly annotated as paaZ (e.g WQ49_RS11500) encodes only one of the two domains found in E.coli paaZ (the domain with semialdehyde dehydrogenase activity) and so is renamed PacL (PMID:21296885) but was also referred to as PaaZ-ALDH in the manuscript. In the same study , a separate A. aromaticum, protein (UniProtKB:Q5P232) with the (R)-hydratase activity was annotated as Ech-Aa and the Burkholderia ortholog was annotated as PaaZ-ECH. . Annotation transferred from: UniProtKB:Q5P232. Dustin Lavallee and Silvia Cardona, University of Manitoba
Apr 30, 2018 BURCENK562V_RS32320 Burkholderia cenocepacia K56-2Valvano New product name: putative (R)-specific oxepin-CoA hydratase. New product name synonym: PaaZ-ECH. New product name confidence: Class 2. New PubMed ID: 21296885. New comment: in E coli, paaZ encodes a bifunctional protein consisting of an N-terminal NADP-dependent aldehyde dehydrogenase domain and a C-terminal MaoC-like (R)-specific enoyl-CoA hydratase domain. In Burkholderia genomes, a gene incorrectly annotated as paaZ (e.g WQ49_RS11500) encodes only one of the two domains found in E.coli paaZ (the domain with semialdehyde dehydrogenase activity) and so is renamed PacL (PMID:21296885) but was also referred to as PaaZ-ALDH in the manuscript. In the same study , a separate A. aromaticum, protein (UniProtKB:Q5P232) with the (R)-hydratase activity was annotated as Ech-Aa and the Burkholderia ortholog was annotated as PaaZ-ECH. . Annotation transferred from: UniProtKB:Q5P232. Dustin Lavallee and Silvia Cardona, University of Manitoba
Apr 30, 2018 BCAS0364 Burkholderia cenocepacia J2315 New product name: putative (R)-specific oxepin-CoA hydratase. New product name synonym: PaaZ-ECH. New product name confidence: Class 2. New PubMed ID: 21296885. New comment: in E coli, paaZ encodes a bifunctional protein consisting of an N-terminal NADP-dependent aldehyde dehydrogenase domain and a C-terminal MaoC-like (R)-specific enoyl-CoA hydratase domain. In Burkholderia genomes, a gene incorrectly annotated as paaZ (e.g WQ49_RS11500) encodes only one of the two domains found in E.coli paaZ (the domain with semialdehyde dehydrogenase activity) and so is renamed PacL (PMID:21296885) but was also referred to as PaaZ-ALDH in the manuscript. In the same study , a separate A. aromaticum, protein (UniProtKB:Q5P232) with the (R)-hydratase activity was annotated as Ech-Aa and the Burkholderia ortholog was annotated as PaaZ-ECH. . Annotation transferred from: UniProtKB:Q5P232. Dustin Lavallee and Silvia Cardona, University of Manitoba
Apr 30, 2018 AK34_RS09175 Burkholderia dolosa AU0158 New product name: putative (R)-specific oxepin-CoA hydratase. New product name synonym: PaaZ-ECH. New product name confidence: Class 2. New PubMed ID: 21296885. New comment: in E coli, paaZ encodes a bifunctional protein consisting of an N-terminal NADP-dependent aldehyde dehydrogenase domain and a C-terminal MaoC-like (R)-specific enoyl-CoA hydratase domain. In Burkholderia genomes, a gene incorrectly annotated as paaZ (e.g WQ49_RS11500) encodes only one of the two domains found in E.coli paaZ (the domain with semialdehyde dehydrogenase activity) and so is renamed PacL (PMID:21296885) but was also referred to as PaaZ-ALDH in the manuscript. In the same study , a separate A. aromaticum, protein (UniProtKB:Q5P232) with the (R)-hydratase activity was annotated as Ech-Aa and the Burkholderia ortholog was annotated as PaaZ-ECH. . Annotation transferred from: UniProtKB:Q5P232. Geoff Winsor, Simon Fraser University. Transferred annotation from the B. cenocepacia annotation provided by D. Lavellee and S. Cardona.
Apr 22, 2009 BCAS0222 Burkholderia cenocepacia J2315 New product name: putative amino acid activating protein. New product name confidence: Class 1. New homology: 94% identity to AfcA [B.cepacia BC11]. New evidence reference (PMID): 9758823. Literature review. Schell, M. A. University of Georgia, Athens, Georgia
Aug 1, 2008 Bcep18194_A4780 New product name: putative dioxygenase, OrbG. New product name confidence: Class 3. New homology: 98% identity to putative dioxygenase, OrbG[B. cenocepacia J2315]. New evidence reference (PMID): 17295049. New evidence reference (PMID): 16672617. Literature review. Thomas, M. S. University of Sheffield, Sheffield, UK
Aug 1, 2008 Bamb_1532 New product name: putative iron transport-related ATP-binding protein, OrbC. New product name confidence: Class 3. New homology: 92% identity to putative iron transport-related ATP-binding protein, OrbC [B. cenocepacia J2315]. New evidence reference (PMID): 17295049. Literature review. Thomas, M. S. University of Sheffield, Sheffield, UK
Aug 1, 2008 Bcep18194_A4781 New product name: putative iron transport-related ATP-binding protein, OrbC. New product name confidence: Class 3. New homology: 95% identity to putative iron transport-related ATP-binding protein, OrbC [B. cenocepacia J2315]. New evidence reference (PMID): 17295049. Literature review. Thomas, M. S. University of Sheffield, Sheffield, UK
Aug 1, 2008 Bcen2424_1635 New product name: putative iron transport-related ATP-binding protein, OrbC. New product name confidence: Class 3. New homology: 97% identity to putative iron transport-related ATP-binding protein, OrbC [B. cenocepacia J2315]. New evidence reference (PMID): 17295049. Literature review. Thomas, M. S. University of Sheffield, Sheffield, UK
Aug 1, 2008 Bcen_1155 New product name: putative iron transport-related ATP-binding protein, OrbC. New product name confidence: Class 3. New homology: 97% identity to putative iron transport-related ATP-binding protein, OrbC [B. cenocepacia J2315]. New evidence reference (PMID): 17295049. Literature review. Thomas, M. S. University of Sheffield, Sheffield, UK
Aug 1, 2008 Bcep18194_A4784 New product name: putative iron transport-related exported protein, OrbB. New product name confidence: Class 3. New homology: 94% identity to putative iron transport-related exported protein, OrbB [B. cenocepacia J2315]. New evidence reference (PMID): 17295049. Literature review. Thomas, M. S. University of Sheffield, Sheffield, UK
Aug 1, 2008 Bamb_1535 New product name: putative iron transport-related exported protein, OrbB. New product name confidence: Class 3. New homology: 94% identity to putative iron transport-related exported protein, OrbB [B. cenocepacia J2315]. New evidence reference (PMID): 17295049. Literature review. Thomas, M. S. University of Sheffield, Sheffield, UK
Aug 1, 2008 Bcen2424_1638 New product name: putative iron transport-related exported protein, OrbB. New product name confidence: Class 3. New homology: 97% identity to putative iron transport-related exported protein, OrbB [B. cenocepacia J2315]. New evidence reference (PMID): 17295049. Literature review. Thomas, M. S. University of Sheffield, Sheffield, UK
Aug 1, 2008 Bcen_1158 New product name: putative iron transport-related exported protein, OrbB. New product name confidence: Class 3. New homology: 97% identity to putative iron transport-related exported protein, OrbB [B. cenocepacia J2315]. New evidence reference (PMID): 17295049. Literature review. Thomas, M. S. University of Sheffield, Sheffield, UK
Aug 1, 2008 Bamb_1533 New product name: putative iron transport-related membrane protein, OrbD. New product name confidence: Class 3. New homology: 93% identity to putative iron transport-related membrane protein, OrbD[B. cenocepacia J2315]. New evidence reference (PMID): 17295049. Literature review. Thomas, M. S. University of Sheffield, Sheffield, UK
Aug 1, 2008 Bcep18194_A4782 New product name: putative iron transport-related membrane protein, OrbD. New product name confidence: Class 3. New homology: 96% identity to putative iron transport-related membrane protein, OrbD[B. cenocepacia J2315]. New evidence reference (PMID): 17295049. Literature review. Thomas, M. S. University of Sheffield, Sheffield, UK
Aug 1, 2008 Bcen_1156 New product name: putative iron transport-related membrane protein, OrbD. New product name confidence: Class 3. New homology: 97% identity to putative iron transport-related membrane protein, OrbD[B. cenocepacia J2315]. New evidence reference (PMID): 17295049. Literature review. Thomas, M. S. University of Sheffield, Sheffield, UK
Aug 1, 2008 Bcen2424_1636 New product name: putative iron transport-related membrane protein, OrbD. New product name confidence: Class 3. New homology: 97% identity to putative iron transport-related membrane protein, OrbD[B. cenocepacia J2315]. New evidence reference (PMID): 17295049. Literature review. Thomas, M. S. University of Sheffield, Sheffield, UK
Sep 15, 2008 Bcep18194_B1816 New product name: putative protein tyrosine kinase. New product name confidence: Class 3. New homology: 33% identity and 53% similarity to BceF [B. cepacia IST408]. New evidence reference (PMID): 17114319. Literature review. Based on article by Moreira, L. M. Instituto Superior Tecnico, Av. Rovisco Pais, Portugal.
Sep 15, 2008 Bcep18194_B2866 New product name: putative protein tyrosine kinase. New product name confidence: Class 3. New homology: 36% identity and 54 % similarity to BceF [B. cepacia IST408]. New evidence reference (PMID): 17114319. Literature review. Based on article by Moreira, L. M. Instituto Superior Tecnico, Av. Rovisco Pais, Portugal.
Sep 15, 2008 Bcep18194_C7398 New product name: putative protein tyrosine kinase. New product name confidence: Class 3. New homology: 37% identity and 56 similarity to BceF [B. cepacia IST408]. New evidence reference (PMID): 17114319. Literature review. Based on article by Moreira, L. M. Instituto Superior Tecnico, Av. Rovisco Pais, Portugal.
Sep 15, 2008 Bcep18194_C7399 New product name: putative protein tyrosine phosphatase. New product name confidence: Class 3. New homology: 35% identity and 55 % similarity to BceD [B. cepacia IST408]. New evidence reference (PMID): 17114319. Literature review. Based on article by Moreira, L. M. Instituto Superior Tecnico, Av. Rovisco Pais, Portugal.
Sep 15, 2008 Bcep18194_B2865 New product name: putative protein tyrosine phosphatase. New product name confidence: Class 3. New homology: 41% identity and 54% similarity to BceD [B. cepacia IST408]. New evidence reference (PMID): 17114319. Literature review. Based on article by Moreira, L. M. Instituto Superior Tecnico, Av. Rovisco Pais, Portugal.
Jan 29, 2010 BCAS0333 Burkholderia cenocepacia J2315 New product name: putative siderophore receptor. New product name confidence: Class 3. Dropped gene name: orbA. Pamela A. Sokol, University of Calgary
Apr 30, 2018 BPSS1517 Burkholderia pseudomallei K96243 New product name: putative type III secretion system chaperone protein (T3SS-3). New PubMed ID: 22092682. New PubMed ID: 28664152. New comment: This gene is part of the type III secretion system T3SS-3 (bsa) gene locus. Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BPSS1521 Burkholderia pseudomallei K96243 New product name: regulator and type III secretion system effector protein BbrD (T3SS-3). New PubMed ID: 25111708. New PubMed ID: 28664152. New PubMed ID: 25635268. New comment: This gene is part of the type III secretion system T3SS-3 (bsa) gene locus. Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BMAA1545 Burkholderia mallei ATCC 23344 New product name: regulator of type III secretion system effector proteins BsaN (T3SS-3). New product name confidence: Class 2. New PubMed ID: 28664152. New PubMed ID: 25085508. New PubMed ID: 20345664. New comment: This gene is part of the Burkholderia mallei type III secretion system T3SS-3 gene locus..Annotation transferred from: BGD:BPSS1546. Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BPSS1553 Burkholderia pseudomallei K96243 New product name: regulator of type III secretion system-3 (T3SS-3) BprP. New product name confidence: Class 2. New PubMed ID: 28664152. New PubMed ID: 25085508. New comment: This gene is part of the type III secretion system T3SS-3 (bsa) gene locus. Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BPSS1554 Burkholderia pseudomallei K96243 New product name: regulator of type III secretion system-3 (T3SS-3) BprQ. New product name confidence: Class 2. New PubMed ID: 28664152. New PubMed ID: 27147217. New comment: This gene is part of the type III secretion system T3SS-3 (bsa) gene locus. Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BPSS1520 Burkholderia pseudomallei K96243 New product name: regulator of type VI secretion system-1 BprC . New PubMed ID: 20345664. New PubMed ID: 21670170. New PubMed ID: 25111708. New PubMed ID: 28664152. New comment: This gene is part of the type III secretion system T3SS-3 (bsa) gene locus. In a bprC mutant, the expression of virA and virG was downregulated to 30% and 42%, respectively, whereas tssA expression was decreased to 4% of wild-type level (PMID:20345664). Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BMAA1529 Burkholderia mallei ATCC 23344 New product name: regulatory protein BprA (T3SS-3). New product name confidence: Class 2. New PubMed ID: 28664152. New comment: This gene is part of the Burkholderia mallei type III secretion system T3SS-3 gene locus..Annotation transferred from: BGD:BPSS1530. Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BPSS1530 Burkholderia pseudomallei K96243 New product name: regulatory protein BprA (T3SS-3). New product name confidence: Class 2. New PubMed ID: 28664152. New comment: This gene is part of the type III secretion system T3SS-3 (bsa) gene locus. Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BPSS1356 Burkholderia pseudomallei K96243 New product name: regulatory protein. New product name confidence: Class 1. New PubMed ID: 24927285. New PubMed ID: 22354666. New comment: Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BTH_II0131 Burkholderia thailandensis E264 ATCC 700388 New product name: Rhs-2. New product name confidence: Class 2. New PubMed ID: 17660433. New PubMed ID: 22007185. New PubMed ID: 17555434. New PubMed ID: 20865170. New comment: This gene is part of cluster known as the type VI secretion system gene cluster tss-2 based on naming convention used for B. pseudomallei described in PMID:17660433, however unlike B. pseudomallei, the numbers following the vgrG and hcp gene match the cluster number (PMID:20865170). Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BTH_II0267 Burkholderia thailandensis E264 ATCC 700388 New product name: Rhs-6. New product name confidence: Class 2. New PubMed ID: 17660433. New PubMed ID: 22007185. New PubMed ID: 17555434. New PubMed ID: 20865170. New comment: This gene is part of cluster known as the type VI secretion system gene cluster tss-6 based on naming convention used for B. pseudomallei described in PMID:17660433, however unlike B. pseudomallei, the numbers following the vgrG and hcp gene match the cluster number (PMID:20865170). Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 ACI79_RS06660 Burkholderia gladioli NGJ1 New product name: T3SS-secreted prophage tail-like protein. New product name confidence: Class 1. New subcellular localization: Host Associated (Class 1). New subcellular localization evidence code (ECO): ECO:0000112. New subcellular localization PMID: 28864820. New PubMed ID: 28864820. New comment: Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 WJ59_RS21240 Burkholderia gladioli MSMB1756 New product name: T3SS-secreted prophage tail-like protein. New product name confidence: Class 2. New subcellular localization: Host Associated (Class 2). New subcellular localization evidence code (ECO): ECO:0000250. New subcellular localization PMID: 28864820. New PubMed ID: 28864820. New comment: .Annotation transferred from: GenBank:AOO34660.1. Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 LA03_RS18415 Burkholderia gladioli UCD-UG_CHAPALOTE New product name: T3SS-secreted prophage tail-like protein. New product name confidence: Class 2. New subcellular localization: Host Associated (Class 2). New subcellular localization evidence code (ECO): ECO:0000250. New subcellular localization PMID: 28864820. New PubMed ID: 28864820. New comment: .Annotation transferred from: GenBank:AOO34660.1. Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 D590_RS24420 Burkholderia gladioli 3848s-5 New product name: T3SS-secreted prophage tail-like protein. New product name confidence: Class 2. New subcellular localization: Host Associated (Class 2). New subcellular localization evidence code (ECO): ECO:0000250. New subcellular localization PMID: 28864820. New PubMed ID: 28864820. New comment: .Annotation transferred from: GenBank:AOO34660.1. Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 bgla_1g01370 Burkholderia gladioli BSR3 New product name: T3SS-secreted prophage tail-like protein. New product name confidence: Class 2. New subcellular localization: Host Associated (Class 2). New subcellular localization evidence code (ECO): ECO:0000250. New subcellular localization PMID: 28864820. New PubMed ID: 28864820. New comment: .Annotation transferred from: GenBank:AOO34660.1. Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 XF14_RS22130 Burkholderia gladioli SN82F6 New product name: T3SS-secreted prophage tail-like protein. New product name confidence: Class 2. New subcellular localization: Host Associated (Class 2). New subcellular localization evidence code (ECO): ECO:0000250. New subcellular localization PMID: 28864820. New PubMed ID: 28864820. New comment: .Annotation transferred from: GenBank:AOO34660.1. Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
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