Burkholderia glumae BGR1, bglu_2g16540 (bceA)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Burkholderia glumae BGR1
GCF_000022645.2|latest |
| Locus Tag |
bglu_2g16540
|
| NCBI Locus Tag | BGLU_RS25815 |
| Name |
bceA
|
| Replicon | chromosome 2 |
| Genomic location | 2078397 - 2079971 (+ strand) |
| Comment | Member of the bce-I gene cluster |
Cross-References
| RefSeq | WP_015877677.1 |
| GI | |
| Entrez | 7903103 |
| NCBI Locus Tag | BGLU_RS25815 |
| NCBI Old Locus Tag | bglu_2g16540 |
| RefSeq | WP_015877677.1,GeneID |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
BceA
|
| Synonyms |
Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase |
| Evidence for Translation | |
| Charge (pH 7) | -5.32 |
| Kyte-Doolittle Hydrophobicity Value | -0.083 |
| Molecular Weight (kDa) | 56238.3 |
| Isoelectric Point (pI) | 6.51 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold 2 Protein Structure Predictions
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
Pathogen Association Analysis
| Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 468 genera
|
Orthologs/Comparative Genomics
| Burkholderia Ortholog Group |
BG003312 (1226 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: bglu_2g16540
Search term: bceA
Search term: BceA
|
Human Homologs
References
|
Distribution of cepacian biosynthesis genes among environmental and clinical Burkholderia strains and role of cepacian exopolysaccharide in resistance to stress conditions.
Ferreira AS, Leitão JH, Silva IN, Pinheiro PF, Sousa SA, Ramos CG, Moreira LM
Appl Environ Microbiol 2010 Jan;76(2):441-50
PubMed ID: 19948863
|
|
The Burkholderia cepacia bceA gene encodes a protein with phosphomannose isomerase and GDP-D-mannose pyrophosphorylase activities.
Sousa SA, Moreira LM, Wopperer J, Eberl L, Sá-Correia I, Leitão JH
Biochem Biophys Res Commun 2007 Feb 2;353(1):200-6
PubMed ID: 17184737
|
|
Functional analysis of the Burkholderia cenocepacia J2315 BceAJ protein with phosphomannose isomerase and GDP-D-mannose pyrophosphorylase activities.
Sousa SA, Moreira LM, Leitão JH
Appl Microbiol Biotechnol 2008 Oct;80(6):1015-22
PubMed ID: 18668237
|