Burkholderia glumae BGR1, bglu_2g16420

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia glumae BGR1
GCF_000022645.2|latest
Locus Tag
bglu_2g16420
NCBI Locus TagBGLU_RS25755
Name
Replicon chromosome 2
Genomic location 2063661 - 2064002 (+ strand)

Cross-References

RefSeq WP_015877665.1
GI
Entrez 7903091
NCBI Locus Tag BGLU_RS25755
NCBI Old Locus Tag bglu_2g16420
RefSeq WP_015877665.1,GeneID

Product

Feature Type CDS
Coding Frame 1
Product Name
peptidyl-prolyl cis-trans isomerase
Synonyms
Evidence for Translation
Charge (pH 7) -2.77
Kyte-Doolittle Hydrophobicity Value -0.048
Molecular Weight (kDa) 11835.4
Isoelectric Point (pI) 4.77

Subcellular localization

Individual Mappings
Localization Confidence PMID
Periplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
2KE0 ISOMERASE 01/21/09 Solution structure of peptidyl-prolyl cis-trans isomerase from Burkholderia pseudomallei BURKHOLDERIA PSEUDOMALLEI NOT SOLUTION NMR 90.3
2Y78 ISOMERASE 01/28/11 Crystal structure of BPSS1823, a Mip-like chaperone from Burkholderia pseudomallei BURKHOLDERIA PSEUDOMALLEI 0.91 X-RAY DIFFRACTION 90.3
2L2S ISOMERASE 08/27/10 Solution structure of peptidyl-prolyl cis-trans isomerase from Burkholderia pseudomallei complexed with 1-{[(4-methylphenyl)thio]acetyl}piperidine BURKHOLDERIA PSEUDOMALLEI NOT SOLUTION NMR 90.3
5V8T ISOMERASE 03/22/17 Crystal structure of SMT fusion Peptidyl-prolyl cis-trans isomerase from Burkholderia pseudomallei complexed with SF354 SACCHAROMYCES CEREVISIAE (STRAIN ATCC 204508 / S288C); BURKHOLDERIA PSEUDOMALLEI 2.1 X-RAY DIFFRACTION 90.2
2KO7 ISOMERASE 09/11/09 Solution structure of peptidyl-prolyl cis-trans isomerase from Burkholderia pseudomallei complexed with Cycloheximide-N-ethylethanoate BURKHOLDERIA PSEUDOMALLEI NOT SOLUTION NMR 90.3
3UQA Isomerase, protein binding 11/19/11 Crystal structure of a SMT fusion Peptidyl-prolyl cis-trans isomerase with surface mutation A54E from Burkholderia pseudomallei complexed with FK506 SACCHAROMYCES CEREVISIAE; BURKHOLDERIA PSEUDOMALLEI 1.55 X-RAY DIFFRACTION 90.2
5KLX ISOMERASE, protein binding 06/26/16 Crystal Structure of SMT Fusion Peptidyl-Prolyl Cis-Trans Isomerase from Burkholderia Pseudomallei Complexed with SF110 SACCHAROMYCES CEREVISIAE; BURKHOLDERIA PSEUDOMALLEI (STRAIN 1710B) 2.45 X-RAY DIFFRACTION 90.2
4GGQ Isomerase, protein binding 08/07/12 Crystal structure of a SMT fusion Peptidyl-prolyl cis-trans isomerase from Burkholderia pseudomallei complexed with CJ40 SACCHAROMYCES CEREVISIAE; BURKHOLDERIA PSEUDOMALLEI 1.95 X-RAY DIFFRACTION 90.2

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 430 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG004859 (637 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: bglu_2g16420

Human Homologs

Ensembl 97, assembly GRCh38.p12
FKBP prolyl isomerase 1A [Source:HGNC Symbol;Acc:HGNC:3711]
E-value: 1.7e-25
Percent Identity: 55.8
Ensembl 97, assembly GRCh38.p12
FKBP prolyl isomerase 1A [Source:HGNC Symbol;Acc:HGNC:3711]
E-value: 1.7e-25
Percent Identity: 55.8

References

No references are associated with this feature.