Burkholderia glumae BGR1, bglu_2g08550 (bceR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia glumae BGR1
GCF_000022645.2|latest
Locus Tag
bglu_2g08550
NCBI Locus TagBGLU_RS22065
Name
bceR
Replicon chromosome 2
Genomic location 1037309 - 1039729 (+ strand)
CommentDisruption of the bceQ and bceR genes, in B. cepacia IST408 (PMID:19948863) resulted in the abolishment of cepacian biosynthesis.
CommentMember of the bce-II gene cluster
CommentNote that another gene (BCAM1493) for a two-component response regulator in B. cenocepacia J2315 was also assigned the name bceR at a later date (PMID:25519693).

Cross-References

RefSeq
GI
Entrez 7902765
NCBI Locus Tag BGLU_RS22065
NCBI Old Locus Tag bglu_2g08550

Product

Feature Type CDS
Coding Frame 1
Product Name
lipopolysaccharide biosynthesys-related glycosyltransferase
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) 11.47
Kyte-Doolittle Hydrophobicity Value 0.011
Molecular Weight (kDa) 87879.7
Isoelectric Point (pI) 9.15

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 573 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG003106 (652 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: bglu_2g08550
Search term: bceR

Human Homologs

References

Distribution of cepacian biosynthesis genes among environmental and clinical Burkholderia strains and role of cepacian exopolysaccharide in resistance to stress conditions.
Ferreira AS, Leitão JH, Silva IN, Pinheiro PF, Sousa SA, Ramos CG, Moreira LM
Appl Environ Microbiol 2010 Jan;76(2):441-50
PubMed ID: 19948863