Burkholderia glumae BGR1, bglu_2g06410 (toxB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia glumae BGR1
GCF_000022645.2|latest
Locus Tag
bglu_2g06410
NCBI Locus TagBGLU_RS21060
Name
toxB
Replicon chromosome 2
Genomic location 769891 - 770649 (+ strand)
CommentMember of the toxoflavin biosynthesis gene cluster

Cross-References

RefSeq
GI
Entrez 7904515
NCBI Locus Tag BGLU_RS21060
NCBI Old Locus Tag bglu_2g06410

Product

Feature Type CDS
Coding Frame 1
Product Name
ToxB
Product Name Confidence: Class 2
Synonyms GTP cyclohydrolase II
Evidence for Translation
Charge (pH 7) 9.76
Kyte-Doolittle Hydrophobicity Value -0.213
Molecular Weight (kDa) 27550.3
Isoelectric Point (pI) 9.74

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 483 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG018054 (348 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: bglu_2g06410
Search term: toxB
Search term: ToxB

Human Homologs

References

Burkholderia glumae ToxA Is a Dual-Specificity Methyltransferase That Catalyzes the Last Two Steps of Toxoflavin Biosynthesis.
Fenwick MK, Philmus B, Begley TP, Ealick SE
Biochemistry 2016 May 17;55(19):2748-59
PubMed ID: 27070241