Burkholderia cenocepacia J2315, BCAM2549 (opcM)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAM2549
NCBI Locus TagQU43_RS67205
Name
opcM
Replicon chromosome 2
Genomic location 2891215 - 2892807 (- strand)

Cross-References

RefSeq
GI
Entrez 6930089
NCBI Locus Tag QU43_RS67205
NCBI Old Locus Tag BCAM2549

Product

Feature Type CDS
Coding Frame 1
Product Name
multidrug efflux system outer membrane protein OpcM
Synonyms
Evidence for Translation
Charge (pH 7) -3.28
Kyte-Doolittle Hydrophobicity Value -0.277
Molecular Weight (kDa) 55666.7
Isoelectric Point (pI) 5.65

Subcellular localization

Individual Mappings
Localization Confidence PMID
Outer Membrane Class 3
Outer Membrane Class 1
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 327 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG004186 (650 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAM2549
Search term: opcM

Human Homologs

References

Nucleotide sequence analysis of a gene from Burkholderia (Pseudomonas) cepacia encoding an outer membrane lipoprotein involved in multiple antibiotic resistance.
Burns JL, Wadsworth CD, Barry JJ, Goodall CP
Antimicrob Agents Chemother 1996 Feb;40(2):307-13
PubMed ID: 8834871