Burkholderia cenocepacia J2315, BCAS0557

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAS0557
NCBI Locus Tag	QU43_RS71450
Name
Replicon	chromosome 3
Genomic location	613450 - 614484 (- strand)

Cross-References

RefSeq	WP_006485987.1
GI	197295402
Entrez	6804383
GI	197295402
INSDC	CAR57488.1
NCBI Locus Tag	QU43_RS71450
NCBI Old Locus Tag	BCAS0557
RefSeq	WP_006485987.1,GeneID
UniParc	UPI00017BB01B
UniProtKB Acc	B4ENV5
UniProtKB ID	B4ENV5_BURCJ
UniRef100	UniRef100_B4ENV5
UniRef50	UniRef50_A0A095FP26
UniRef90	UniRef90_A0A095FP26

Product

Feature Type	CDS
Coding Frame	1
Product Name	metallo-beta-lactamase superfamily protein
Synonyms
Evidence for Translation
Charge (pH 7)	3.52
Kyte-Doolittle Hydrophobicity Value	0.065
Molecular Weight (kDa)	36301.9
Isoelectric Point (pI)	8.03

Subcellular localization

Individual Mappings	Localization Confidence PMID Unknown (This protein may have multiple localization sites) Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 245 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG001859 (602 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAS0557 Search term: metallo-beta-lactamase superfamily protein

Human Homologs

Ensembl 97, assembly GRCh38.p12	ENSP00000428801 lactamase beta 2 [Source:HGNC Symbol;Acc:HGNC:18512] E-value: 3.5e-05 Percent Identity: 40.9
Ensembl 97, assembly GRCh38.p12	ENSP00000276590 lactamase beta 2 [Source:HGNC Symbol;Acc:HGNC:18512] E-value: 3.5e-05 Percent Identity: 40.9

References