Burkholderia cenocepacia J2315, BCAS0293 (aidA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAS0293
NCBI Locus TagQU43_RS70145
Name
aidA
Replicon chromosome 3
Genomic location 328534 - 329037 (- strand)

Cross-References

RefSeq WP_006483191.1
GI 197295142
Entrez 6804192
GI 197295142
INSDC CAR57225.1
NCBI Locus Tag QU43_RS70145
NCBI Old Locus Tag BCAS0293
RefSeq WP_006483191.1,GeneID
UniParc UPI000052DF38
UniProtKB Acc B4EQ59
UniProtKB ID B4EQ59_BURCJ
UniRef100 UniRef100_A0A071M2V9
UniRef50 UniRef50_Q39MR0
UniRef90 UniRef90_Q39MR0

Product

Feature Type CDS
Coding Frame 1
Product Name
nematocidal protein AidA
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) -0.66
Kyte-Doolittle Hydrophobicity Value -0.266
Molecular Weight (kDa) 18871.3
Isoelectric Point (pI) 6.50

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Cytoplasmic Class 1
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 13 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG004444 (417 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAS0293
Search term: aidA

Human Homologs

References

Identification of a novel virulence factor in Burkholderia cenocepacia H111 required for efficient slow killing of Caenorhabditis elegans.
Huber B, Feldmann F, Köthe M, Vandamme P, Wopperer J, Riedel K, Eberl L
Infect Immun 2004 Dec;72(12):7220-30
PubMed ID: 15557647
Reciprocal regulation by the CepIR and CciIR quorum sensing systems in Burkholderia cenocepacia.
O'Grady EP, Viteri DF, Malott RJ, Sokol PA
BMC Genomics 2009 Sep 17;10:441
PubMed ID: 19761612