Burkholderia cenocepacia J2315, BCAS0223 (afcC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAS0223
NCBI Locus TagQU43_RS69795
Name
afcC
Replicon chromosome 3
Genomic location 241076 - 242071 (+ strand)

Cross-References

RefSeq YP_002153613.1
GI 197295072
Entrez 6804594
GI 197295072
INSDC CAR57155.1
NCBI Locus Tag QU43_RS69795
NCBI Old Locus Tag BCAS0223
RefSeq YP_002153613.1
UniParc UPI00017BB24F
UniProtKB Acc B4EPY9
UniProtKB ID B4EPY9_BURCJ
UniRef100 UniRef100_A0A0D1DRR1
UniRef50 UniRef50_G7HPV3
UniRef90 UniRef90_G7HPV3

Product

Feature Type CDS
Coding Frame 1
Product Name
putative fatty acid desaturase
Product Name Confidence: Class 2
Synonyms AfcC
Evidence for Translation
Charge (pH 7) 12.28
Kyte-Doolittle Hydrophobicity Value 0.101
Molecular Weight (kDa) 37333.1
Isoelectric Point (pI) 9.87

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 40 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG005275 (85 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAS0223
Search term: afcC

Human Homologs

References

Characterization of genes involved in biosynthesis of a novel antibiotic from Burkholderia cepacia BC11 and their role in biological control of Rhizoctonia solani.
Kang Y, Carlson R, Tharpe W, Schell MA
Appl Environ Microbiol 1998 Oct;64(10):3939-47
PubMed ID: 9758823