Burkholderia cenocepacia J2315, BCAS0223 (afcC)

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAS0223
NCBI Locus Tag	QU43_RS69795
Name	afcC
Replicon	chromosome 3
Genomic location	241076 - 242071 (+ strand)

Cross-References

RefSeq	YP_002153613.1
GI	197295072
Entrez	6804594
GI	197295072
INSDC	CAR57155.1
NCBI Locus Tag	QU43_RS69795
NCBI Old Locus Tag	BCAS0223
RefSeq	YP_002153613.1
UniParc	UPI00017BB24F
UniProtKB Acc	B4EPY9
UniProtKB ID	B4EPY9_BURCJ
UniRef100	UniRef100_A0A0D1DRR1
UniRef50	UniRef50_G7HPV3
UniRef90	UniRef90_G7HPV3

Product

Feature Type	CDS
Coding Frame	1
Product Name	putative fatty acid desaturase Product Name Confidence: Class 2
Synonyms	AfcC
Evidence for Translation
Charge (pH 7)	12.28
Kyte-Doolittle Hydrophobicity Value	0.101
Molecular Weight (kDa)	37333.1
Isoelectric Point (pI)	9.87

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Membrane Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 40 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG005275 (85 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAS0223 Search term: afcC Search term: putative fatty acid desaturase

Human Homologs

References

Characterization of genes involved in biosynthesis of a novel antibiotic from Burkholderia cepacia BC11 and their role in biological control of Rhizoctonia solani. Kang Y, Carlson R, Tharpe W, Schell MA Appl Environ Microbiol 1998 Oct;64(10):3939-47 PubMed ID: 9758823