Burkholderia cenocepacia J2315, BCAS0081

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAS0081
NCBI Locus TagQU43_RS69065
Name
Replicon chromosome 3
Genomic location 89870 - 91723 (- strand)

Cross-References

RefSeq WP_006490970.1
GI 197294933
Entrez 6804576
GI 197294933
INSDC CAR57014.1
NCBI Locus Tag QU43_RS69065
NCBI Old Locus Tag BCAS0081
RefSeq WP_006490970.1,GeneID
UniParc UPI00017BB146
UniProtKB Acc B4EPJ8
UniProtKB ID B4EPJ8_BURCJ
UniRef100 UniRef100_B4EPJ8
UniRef50 UniRef50_Q57180
UniRef90 UniRef90_Q39LE8

Product

Feature Type CDS
Coding Frame 1
Product Name
ABC transporter ATP-binding membrane protein
Synonyms
Evidence for Translation
Charge (pH 7) -2.95
Kyte-Doolittle Hydrophobicity Value 0.221
Molecular Weight (kDa) 67366.0
Isoelectric Point (pI) 6.67

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 669 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG006779 (280 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAS0081

Human Homologs

Ensembl 97, assembly GRCh38.p12
ATP binding cassette subfamily B member 6 (Langereis blood group) [Source:HGNC Symbol;Acc:HGNC:47]
E-value: 2.8e-61
Percent Identity: 39.2
Ensembl 97, assembly GRCh38.p12
ATP binding cassette subfamily B member 6 (Langereis blood group) [Source:HGNC Symbol;Acc:HGNC:47]
E-value: 2.8e-61
Percent Identity: 39.2

References

Spontaneous and evolutionary changes in the antibiotic resistance of Burkholderia cenocepacia observed by global gene expression analysis.
Sass A, Marchbank A, Tullis E, Lipuma JJ, Mahenthiralingam E
BMC Genomics 2011 Jul 22;12:373
PubMed ID: 21781329