Burkholderia cenocepacia J2315, BCAM2754

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAM2754
NCBI Locus Tag	QU43_RS68230
Name
Replicon	chromosome 2
Genomic location	3113795 - 3114547 (+ strand)

Cross-References

RefSeq	WP_006485028.1
GI	206564592
Entrez	6930260
GI	206564592
INSDC	CAR56618.1
NCBI Locus Tag	QU43_RS68230
NCBI Old Locus Tag	BCAM2754
RefSeq	WP_006485028.1,GeneID
UniParc	UPI00017BA374
UniProtKB Acc	B4ELF3
UniProtKB ID	B4ELF3_BURCJ
UniRef100	UniRef100_A0A095E8V6
UniRef50	UniRef50_G8NVB8
UniRef90	UniRef90_A2W2B2

Product

Feature Type	CDS
Coding Frame	1
Product Name	putative ketoreductase
Synonyms
Evidence for Translation
Charge (pH 7)	-2.07
Kyte-Doolittle Hydrophobicity Value	0.336
Molecular Weight (kDa)	25402.6
Isoelectric Point (pI)	6.12

Subcellular localization

Individual Mappings	Localization Confidence PMID Unknown (This protein may have multiple localization sites) Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 652 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG003028 (1147 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAM2754 Search term: putative ketoreductase

Human Homologs

Ensembl 97, assembly GRCh38.p12	ENSP00000250383 dehydrogenase/reductase 2 [Source:HGNC Symbol;Acc:HGNC:18349] E-value: 5.7e-21 Percent Identity: 33.9
Ensembl 97, assembly GRCh38.p12	ENSP00000326219 dehydrogenase/reductase 4 [Source:HGNC Symbol;Acc:HGNC:16985] E-value: 5.7e-21 Percent Identity: 33.2
Ensembl 97, assembly GRCh38.p12	ENSP00000494364 dehydrogenase/reductase 4 [Source:HGNC Symbol;Acc:HGNC:16985] E-value: 5.7e-21 Percent Identity: 33.2

References