Burkholderia cenocepacia J2315, BCAM2371 (sigI)

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAM2371
NCBI Locus Tag	QU43_RS66240
Name	sigI
Replicon	chromosome 2
Genomic location	2666931 - 2668817 (+ strand)

Cross-References

RefSeq	WP_006486125.1
GI	206564209
Entrez	6930492
GI	206564209
INSDC	CAR56232.1
NCBI Locus Tag	QU43_RS66240
NCBI Old Locus Tag	BCAM2371
RefSeq	WP_006486125.1,GeneID
UniParc	UPI00017BA29D
UniProtKB Acc	B4EHY9
UniProtKB ID	B4EHY9_BURCJ
UniRef100	UniRef100_B4EHY9
UniRef50	UniRef50_A0A095EQD8
UniRef90	UniRef90_A2W399

Product

Feature Type	CDS
Coding Frame	1
Product Name	putative RNA polymerase sigma-subunit Product Name Confidence: Class 1
Synonyms	sigma factor 70 sigI
Evidence for Translation
Charge (pH 7)	-7.57
Kyte-Doolittle Hydrophobicity Value	-0.142
Molecular Weight (kDa)	67692.5
Isoelectric Point (pI)	6.30

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 591 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG005277 (156 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAM2371 Search term: sigI Search term: putative RNA polymerase sigma-subunit

Human Homologs

References

Architecture of Burkholderia cepacia complex sigma70 gene family: evidence of alternative primary and clade-specific factors, and genomic instability. Menard A, de Los Santos PE, Graindorge A, Cournoyer B BMC Genomics 2007 Sep 4;8:308 PubMed ID: 17784948