Burkholderia cenocepacia J2315, BCAM2371 (sigI)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAM2371
NCBI Locus TagQU43_RS66240
Name
sigI
Replicon chromosome 2
Genomic location 2666931 - 2668817 (+ strand)

Cross-References

RefSeq WP_006486125.1
GI 206564209
Entrez 6930492
GI 206564209
INSDC CAR56232.1
NCBI Locus Tag QU43_RS66240
NCBI Old Locus Tag BCAM2371
RefSeq WP_006486125.1,GeneID
UniParc UPI00017BA29D
UniProtKB Acc B4EHY9
UniProtKB ID B4EHY9_BURCJ
UniRef100 UniRef100_B4EHY9
UniRef50 UniRef50_A0A095EQD8
UniRef90 UniRef90_A2W399

Product

Feature Type CDS
Coding Frame 1
Product Name
putative RNA polymerase sigma-subunit
Product Name Confidence: Class 1
Synonyms sigma factor 70 sigI
Evidence for Translation
Charge (pH 7) -7.57
Kyte-Doolittle Hydrophobicity Value -0.142
Molecular Weight (kDa) 67692.5
Isoelectric Point (pI) 6.30

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 591 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG005277 (156 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAM2371
Search term: sigI

Human Homologs

References

Architecture of Burkholderia cepacia complex sigma70 gene family: evidence of alternative primary and clade-specific factors, and genomic instability.
Menard A, de Los Santos PE, Graindorge A, Cournoyer B
BMC Genomics 2007 Sep 4;8:308
PubMed ID: 17784948