Burkholderia cenocepacia J2315, BCAM2234 (pchB)

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAM2234
NCBI Locus Tag	QU43_RS65535
Name	pchB
Replicon	chromosome 2
Genomic location	2504768 - 2505073 (+ strand)

Cross-References

RefSeq	WP_006484772.1
GI	206564069
Entrez	6930588
GI	206564069
INSDC	CAR56091.1
NCBI Locus Tag	QU43_RS65535
NCBI Old Locus Tag	BCAM2234
RefSeq	WP_006484772.1,GeneID
UniParc	UPI00017BA022
UniProtKB Acc	B4EGG5
UniProtKB ID	B4EGG5_BURCJ
UniRef100	UniRef100_A0A095E8K4
UniRef50	UniRef50_Q51507
UniRef90	UniRef90_Q399S9

Product

Feature Type	CDS
Coding Frame	1
Product Name	isochorismate-pyruvate lyase
Synonyms
Evidence for Translation
Charge (pH 7)	-1.04
Kyte-Doolittle Hydrophobicity Value	-0.425
Molecular Weight (kDa)	11510.9
Isoelectric Point (pI)	5.14

Subcellular localization

Individual Mappings	Localization Confidence PMID Unknown Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 73 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG006696 (378 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAM2234 Search term: pchB Search term: isochorismate-pyruvate lyase

Human Homologs

References

Dihydroaeruginoic acid synthetase and pyochelin synthetase, products of the pchEF genes, are induced by extracellular pyochelin in Pseudomonas aeruginosa. Reimmann C, Serino L, Beyeler M, Haas D Microbiology 1998 Nov;144 ( Pt 11):3135-48 PubMed ID: 9846750

Erratum in: J Bacteriol. 2009 Apr;191(8):2907. The genome of Burkholderia cenocepacia J2315, an epidemic pathogen of cystic fibrosis patients. J Bacteriol. 2009 Jan;191(1):261-77. PubMed ID: 18931103