Burkholderia cenocepacia J2315, BCAM2194 (mmsA)

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAM2194
NCBI Locus Tag	QU43_RS65335
Name	mmsA
Replicon	chromosome 2
Genomic location	2452691 - 2454220 (- strand)

Cross-References

RefSeq	WP_006482814.1
GI	206564031
Entrez	6930555
GI	206564031
INSDC	CAR56052.1
NCBI Locus Tag	QU43_RS65335
NCBI Old Locus Tag	BCAM2194
RefSeq	WP_006482814.1,GeneID
UniParc	UPI00017BA21E
UniProtKB Acc	B4EGC6
UniProtKB ID	B4EGC6_BURCJ
UniRef100	UniRef100_B4EGC6
UniRef50	UniRef50_Q02252
UniRef90	UniRef90_B4EGC6

Product

Feature Type	CDS
Coding Frame	1
Product Name	methylmalonate-semialdehyde dehydrogenase
Synonyms
Evidence for Translation
Charge (pH 7)	-4.97
Kyte-Doolittle Hydrophobicity Value	0.114
Molecular Weight (kDa)	54032.8
Isoelectric Point (pI)	6.07

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 595 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG003167 (926 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAM2194 Search term: mmsA Search term: methylmalonate-semialdehyde dehydrogenase

Human Homologs

Ensembl 97, assembly GRCh38.p12

ENSP00000450436 aldehyde dehydrogenase 6 family member A1 [Source:HGNC Symbol;Acc:HGNC:7179] E-value: 1.7e-160 Percent Identity: 58.8

References