Burkholderia cenocepacia J2315, BCAM2187 (macB)

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAM2187
NCBI Locus Tag	QU43_RS65300
Name	macB
Replicon	chromosome 2
Genomic location	2443695 - 2445740 (+ strand)

Cross-References

RefSeq	WP_006483164.1
GI	206564024
Entrez	6929776
GI	206564024
INSDC	CAR56045.1
NCBI Locus Tag	QU43_RS65300
NCBI Old Locus Tag	BCAM2187
RefSeq	WP_006483164.1,GeneID
UniParc	UPI00017BA153
UniProtKB Acc	B4EFY4
UniProtKB ID	B4EFY4_BURCJ
UniRef100	UniRef100_B4EFY4
UniRef50	UniRef50_Q1BPZ6
UniRef90	UniRef90_Q399M3

Product

Feature Type	CDS
Coding Frame	1
Product Name	putative macrolide-specific ABC-type efflux carrier protein
Synonyms
Evidence for Translation
Charge (pH 7)	6.72
Kyte-Doolittle Hydrophobicity Value	0.141
Molecular Weight (kDa)	73046.3
Isoelectric Point (pI)	8.47

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Membrane Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 669 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG000213 (849 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAM2187 Search term: macB Search term: putative macrolide-specific ABC-type efflux carrier protein

Human Homologs

Ensembl 97, assembly GRCh38.p12

ENSP00000384881 ATP binding cassette subfamily B member 5 [Source:HGNC Symbol;Acc:HGNC:46] E-value: 1.0e-16 Percent Identity: 30.9

References