Burkholderia cenocepacia J2315, BCAM2141

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAM2141
NCBI Locus TagQU43_RS65070
Name
Replicon chromosome 2
Genomic location 2379255 - 2381474 (- strand)

Cross-References

RefSeq WP_006490348.1
GI 206563978
Entrez 6929735
GI 206563978
INSDC CAR55999.1
NCBI Locus Tag QU43_RS65070
NCBI Old Locus Tag BCAM2141
RefSeq WP_006490348.1,GeneID
UniParc UPI00017BA199
UniProtKB Acc B4EFT8
UniProtKB ID B4EFT8_BURCJ
UniRef100 UniRef100_B4EFT8
UniRef50 UniRef50_D8P5A5
UniRef90 UniRef90_B4EFT8

Product

Feature Type CDS
Coding Frame 1
Product Name
ABC transporter ATP-binding membrane protein
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) 4.62
Kyte-Doolittle Hydrophobicity Value 0.315
Molecular Weight (kDa) 79308.4
Isoelectric Point (pI) 8.63

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 669 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002924 (998 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAM2141

Human Homologs

Ensembl 97, assembly GRCh38.p12
ATP binding cassette subfamily B member 4 [Source:HGNC Symbol;Acc:HGNC:45]
E-value: 5.6e-32
Percent Identity: 27.1
Ensembl 97, assembly GRCh38.p12
ATP binding cassette subfamily B member 4 [Source:HGNC Symbol;Acc:HGNC:45]
E-value: 5.6e-32
Percent Identity: 27.1

References

Identification of functions linking quorum sensing with biofilm formation in Burkholderia cenocepacia H111.
Inhülsen S, Aguilar C, Schmid N, Suppiger A, Riedel K, Eberl L
Microbiologyopen 2012 Jun;1(2):225-42
PubMed ID: 22950027