Burkholderia cenocepacia J2315, BCAM2048 (bcscN)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAM2048
NCBI Locus TagQU43_RS64600
Name
bcscN
Replicon chromosome 2
Genomic location 2279761 - 2281134 (- strand)

Cross-References

RefSeq WP_006487564.1
GI 206563889
Entrez 6929667
GI 206563889
INSDC CAR55907.1
NCBI Locus Tag QU43_RS64600
NCBI Old Locus Tag BCAM2048
RefSeq WP_006487564.1,GeneID
UniParc UPI000000545C
UniProtKB Acc B4EN91
UniProtKB ID B4EN91_BURCJ
UniRef100 UniRef100_Q8VP15
UniRef50 UniRef50_P40291
UniRef90 UniRef90_Q1BPP2

Product

Feature Type CDS
Coding Frame 1
Product Name
type III secretion ssytem protein
Synonyms
Evidence for Translation
Charge (pH 7) -3.87
Kyte-Doolittle Hydrophobicity Value -0.008
Molecular Weight (kDa) 48935.3
Isoelectric Point (pI) 6.26

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 666 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG003796 (728 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAM2048
Search term: bcscN

Human Homologs

Ensembl 97, assembly GRCh38.p12
ATP synthase F1 subunit beta [Source:HGNC Symbol;Acc:HGNC:830]
E-value: 6.3e-34
Percent Identity: 28.8

References

A putative type III secretion gene cluster is widely distributed in the Burkholderia cepacia complex but absent from genomovar I.
Parsons YN, Glendinning KJ, Thornton V, Hales BA, Hart CA, Winstanley C
FEMS Microbiol Lett 2001 Sep 11;203(1):103-8
PubMed ID: 11557147
Sequence divergence in type III secretion gene clusters of the Burkholderia cepacia complex.
Glendinning KJ, Parsons YN, Duangsonk K, Hales BA, Humphreys D, Hart CA, Winstanley C
FEMS Microbiol Lett 2004 Jun 15;235(2):229-35
PubMed ID: 15183868