Burkholderia cenocepacia J2315, BCAM1340 (manC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAM1340
NCBI Locus TagQU43_RS61060
Name
manC
Replicon chromosome 2
Genomic location 1486332 - 1487852 (- strand)

Cross-References

RefSeq WP_006490764.1
GI 206563192
Entrez 6929007
GI 206563192
INSDC CAR55197.1
NCBI Locus Tag QU43_RS61060
NCBI Old Locus Tag BCAM1340
RefSeq WP_006490764.1,GeneID
UniParc UPI00017BA114
UniProtKB Acc B4EHY1
UniProtKB ID B4EHY1_BURCJ
UniRef100 UniRef100_B4EHY1
UniRef50 UniRef50_P24174
UniRef90 UniRef90_G7HBN3

Product

Feature Type CDS
Coding Frame 1
Product Name
mannose-1-phosphate guanylyltransferase
Synonyms
Evidence for Translation
Charge (pH 7) -14.72
Kyte-Doolittle Hydrophobicity Value -0.179
Molecular Weight (kDa) 55392.1
Isoelectric Point (pI) 5.16

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 468 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG003312 (1226 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAM1340
Search term: manC

Human Homologs

References

The exopolysaccharide gene cluster Bcam1330-Bcam1341 is involved in Burkholderia cenocepacia biofilm formation, and its expression is regulated by c-di-GMP and Bcam1349.
Fazli M, McCarthy Y, Givskov M, Ryan RP, Tolker-Nielsen T
Microbiologyopen 2013 Feb;2(1):105-22
PubMed ID: 23281338