Burkholderia cenocepacia J2315, BCAM1008 (bceR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAM1008
NCBI Locus TagQU43_RS59420
Name
bceR
Replicon chromosome 2
Genomic location 1118486 - 1120954 (+ strand)
CommentDisruption of the bceQ and bceR genes, in B. cepacia IST408 (PMID:19948863) resulted in the abolishment of cepacian biosynthesis.
CommentMember of the bce-II gene cluster
CommentNote that another gene (BCAM1493) for a two-component response regulator in B. cenocepacia J2315 was also assigned the name bceR at a later date (PMID:25519693).

Cross-References

RefSeq WP_012493216.1
GI 206562863
Entrez 6928716
GI 206562863
INSDC CAR54865.1
NCBI Locus Tag QU43_RS59420
NCBI Old Locus Tag BCAM1008
RefSeq WP_012493216.1,GeneID
UniParc UPI00017B9D27
UniProtKB Acc B4EFL6
UniProtKB ID B4EFL6_BURCJ
UniRef100 UniRef100_B4EFL6
UniRef50 UniRef50_A3P7L1
UniRef90 UniRef90_Q393Z4

Product

Feature Type CDS
Coding Frame 1
Product Name
glycosyltransferase
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) 12.63
Kyte-Doolittle Hydrophobicity Value 0.004
Molecular Weight (kDa) 89537.8
Isoelectric Point (pI) 8.99

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 564 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG003106 (652 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAM1008
Search term: bceR

References

Distribution of cepacian biosynthesis genes among environmental and clinical Burkholderia strains and role of cepacian exopolysaccharide in resistance to stress conditions.
Ferreira AS, Leitão JH, Silva IN, Pinheiro PF, Sousa SA, Ramos CG, Moreira LM
Appl Environ Microbiol 2010 Jan;76(2):441-50
PubMed ID: 19948863