Burkholderia cenocepacia J2315, BCAM1007 (bceQ)

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAM1007
NCBI Locus Tag	QU43_RS59415
Name	bceQ
Replicon	chromosome 2
Genomic location	1117023 - 1118489 (+ strand)
Comment	Member of the bce-II gene cluster
Comment	Disruption of the bceQ and bceR genes, in B. cepacia IST408 (PMID:19948863) resulted in the abolishment of cepacian biosynthesis

Cross-References

RefSeq	WP_006491256.1
GI	206562862
Entrez	6928715
GI	206562862
INSDC	CAR54864.1
NCBI Locus Tag	QU43_RS59415
NCBI Old Locus Tag	BCAM1007
RefSeq	WP_006491256.1,GeneID
UniParc	UPI00017B9D26
UniProtKB Acc	B4EFL5
UniProtKB ID	B4EFL5_BURCJ
UniRef100	UniRef100_A0A095E907
UniRef50	UniRef50_Q13YU9
UniRef90	UniRef90_Q393Z3

Product

Feature Type	CDS
Coding Frame	1
Product Name	putative polysaccharide biosynthesis protein Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7)	11.88
Kyte-Doolittle Hydrophobicity Value	0.853
Molecular Weight (kDa)	52443.7
Isoelectric Point (pI)	10.22

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Membrane Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 55 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG003105 (651 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAM1007 Search term: bceQ Search term: putative polysaccharide biosynthesis protein

Human Homologs

References

Distribution of cepacian biosynthesis genes among environmental and clinical Burkholderia strains and role of cepacian exopolysaccharide in resistance to stress conditions. Ferreira AS, Leitão JH, Silva IN, Pinheiro PF, Sousa SA, Ramos CG, Moreira LM Appl Environ Microbiol 2010 Jan;76(2):441-50 PubMed ID: 19948863