Burkholderia cenocepacia J2315, BCAM0999 (metZ)

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAM0999
NCBI Locus Tag	QU43_RS59380
Name	metZ
Replicon	chromosome 2
Genomic location	1106665 - 1107855 (+ strand)

Cross-References

RefSeq	WP_006491257.1
GI	206562855
Entrez	6930619
GI	206562855
INSDC	CAR54857.1
NCBI Locus Tag	QU43_RS59380
NCBI Old Locus Tag	BCAM0999
RefSeq	WP_006491257.1,GeneID
UniParc	UPI00017B9D1F
UniProtKB Acc	B4EFK8
UniProtKB ID	B4EFK8_BURCJ
UniRef100	UniRef100_B4EFK8
UniRef50	UniRef50_P55218
UniRef90	UniRef90_B4EFK8

Product

Feature Type	CDS
Coding Frame	1
Product Name	O-succinylhomoserine sulfhydrylase
Synonyms
Evidence for Translation
Charge (pH 7)	-5.94
Kyte-Doolittle Hydrophobicity Value	-0.004
Molecular Weight (kDa)	42611.9
Isoelectric Point (pI)	5.84

Subcellular localization

Individual Mappings	Localization Confidence PMID Unknown (This protein may have multiple localization sites) Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 567 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG003101 (648 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAM0999 Search term: metZ Search term: O-succinylhomoserine sulfhydrylase

Human Homologs

Ensembl 97, assembly GRCh38.p12

ENSP00000359976 cystathionine gamma-lyase [Source:HGNC Symbol;Acc:HGNC:2501] E-value: 3.5e-57 Percent Identity: 34.6

References