Burkholderia cenocepacia J2315, BCAM0864 (bceK)

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAM0864
NCBI Locus Tag	QU43_RS58700
Name	bceK
Replicon	chromosome 2
Genomic location	954151 - 955317 (+ strand)
Comment	Member of the bce-I gene cluster

Cross-References

RefSeq	WP_006482818.1
GI	206562720
Entrez	6930379
GI	206562720
INSDC	CAR54722.1
NCBI Locus Tag	QU43_RS58700
NCBI Old Locus Tag	BCAM0864
RefSeq	WP_006482818.1,GeneID
UniParc	UPI00017B9A2D
UniProtKB Acc	B4EMY3
UniProtKB ID	B4EMY3_BURCJ
UniRef100	UniRef100_B4EMY3
UniRef50	UniRef50_Q393I8
UniRef90	UniRef90_Q393I8

Product

Feature Type	CDS
Coding Frame	1
Product Name	BceK Product Name Confidence: Class 2
Synonyms	glycosyltransferase
Evidence for Translation
Charge (pH 7)	2.87
Kyte-Doolittle Hydrophobicity Value	0.023
Molecular Weight (kDa)	41344.0
Isoelectric Point (pI)	8.23

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 589 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG004856 (636 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAM0864 Search term: bceK Search term: BceK

Human Homologs

References

Identification and physical organization of the gene cluster involved in the biosynthesis of Burkholderia cepacia complex exopolysaccharide. Moreira LM, Videira PA, Sousa SA, Leitão JH, Cunha MV, Sá-Correia I Biochem Biophys Res Commun 2003 Dec 12;312(2):323-33 PubMed ID: 14637140

Distribution of cepacian biosynthesis genes among environmental and clinical Burkholderia strains and role of cepacian exopolysaccharide in resistance to stress conditions. Ferreira AS, Leitão JH, Silva IN, Pinheiro PF, Sousa SA, Ramos CG, Moreira LM Appl Environ Microbiol 2010 Jan;76(2):441-50 PubMed ID: 19948863

Insights into the role of extracellular polysaccharides in Burkholderia adaptation to different environments. Ferreira AS, Silva IN, Oliveira VH, Cunha R, Moreira LM Front Cell Infect Microbiol 2011;1:16 PubMed ID: 22919582