Burkholderia cenocepacia J2315, BCAM0858 (bceE)

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAM0858
NCBI Locus Tag	QU43_RS58670
Name	bceE
Replicon	chromosome 2
Genomic location	945828 - 947006 (+ strand)
Comment	Member of the bce-I gene cluster

Cross-References

RefSeq	WP_006482941.1
GI	206562714
Entrez	6930373
GI	206562714
INSDC	CAR54716.1
NCBI Locus Tag	QU43_RS58670
NCBI Old Locus Tag	BCAM0858
RefSeq	WP_006482941.1,GeneID
UniParc	UPI00017B99F1
UniProtKB Acc	B4EMX7
UniProtKB ID	B4EMX7_BURCJ
UniRef100	UniRef100_A0A095F7Y7
UniRef50	UniRef50_Q3JK30
UniRef90	UniRef90_Q0GYW3

Product

Feature Type	CDS
Coding Frame	1
Product Name	putative polysaccharide biosynthesis/export lipoprotein Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7)	3.69
Kyte-Doolittle Hydrophobicity Value	-0.228
Molecular Weight (kDa)	42848.7
Isoelectric Point (pI)	9.10

Subcellular localization

Individual Mappings	Localization Confidence PMID Outer Membrane Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 305 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG004850 (650 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAM0858 Search term: bceE Search term: putative polysaccharide biosynthesis/export lipoprotein

Human Homologs

References

Identification and physical organization of the gene cluster involved in the biosynthesis of Burkholderia cepacia complex exopolysaccharide. Moreira LM, Videira PA, Sousa SA, Leitão JH, Cunha MV, Sá-Correia I Biochem Biophys Res Commun 2003 Dec 12;312(2):323-33 PubMed ID: 14637140

Distribution of cepacian biosynthesis genes among environmental and clinical Burkholderia strains and role of cepacian exopolysaccharide in resistance to stress conditions. Ferreira AS, Leitão JH, Silva IN, Pinheiro PF, Sousa SA, Ramos CG, Moreira LM Appl Environ Microbiol 2010 Jan;76(2):441-50 PubMed ID: 19948863