Burkholderia cenocepacia J2315, BCAM0580 (rpfR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAM0580
NCBI Locus TagQU43_RS57290
Name
rpfR
Replicon chromosome 2
Genomic location 643913 - 645916 (+ strand)

Cross-References

RefSeq WP_006488779.1
GI 206562440
Entrez 6928349
GI 206562440
INSDC CAR54438.1
NCBI Locus Tag QU43_RS57290
NCBI Old Locus Tag BCAM0580
RefSeq WP_006488779.1,GeneID
UniParc UPI00017B9A6F
UniProtKB Acc B4EKM4
UniProtKB ID B4EKM4_BURCJ
UniRef100 UniRef100_A0A0D1BP90
UniRef50 UniRef50_P77334
UniRef90 UniRef90_A0A095FRU3

Product

Feature Type CDS
Coding Frame 1
Product Name
Cis-2-dodecenoic acid receptor RpfR
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) -17.81
Kyte-Doolittle Hydrophobicity Value -0.034
Molecular Weight (kDa) 73390.7
Isoelectric Point (pI) 5.23

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 459 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG004646 (511 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAM0580
Search term: rpfR

Human Homologs

References

Cis-2-dodecenoic acid receptor RpfR links quorum-sensing signal perception with regulation of virulence through cyclic dimeric guanosine monophosphate turnover.
Deng Y, Schmid N, Wang C, Wang J, Pessi G, Wu D, Lee J, Aguilar C, Ahrens CH, Chang C, Song H, Eberl L, Zhang LH
Proc Natl Acad Sci U S A 2012 Sep 18;109(38):15479-84
PubMed ID: 22949660