Burkholderia cenocepacia J2315, BCAM0448 (cusF)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAM0448
NCBI Locus TagQU43_RS56635
Name
cusF
Replicon chromosome 2
Genomic location 503091 - 503447 (+ strand)

Cross-References

RefSeq WP_006484544.1
GI 206562311
Entrez 6928225
GI 206562311
INSDC CAR54306.1
NCBI Locus Tag QU43_RS56635
NCBI Old Locus Tag BCAM0448
RefSeq WP_006484544.1,GeneID
UniParc UPI00017B9CB8
UniProtKB Acc B4EJH1
UniProtKB ID B4EJH1_BURCJ
UniRef100 UniRef100_A0A0D1CBC3
UniRef50 UniRef50_Q2T3U7
UniRef90 UniRef90_G7HEY9

Product

Feature Type CDS
Coding Frame 1
Product Name
CusF
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) -2.29
Kyte-Doolittle Hydrophobicity Value 0.049
Molecular Weight (kDa) 12210.1
Isoelectric Point (pI) 5.61

Subcellular localization

Individual Mappings
Localization Confidence PMID
Periplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 68 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG004573 (1080 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAM0448
Search term: cusF
Search term: CusF

Human Homologs

References

Copper resistance genes of Burkholderia cenocepacia H111 identified by transposon sequencing.
Higgins S, Gualdi S, Pinto-Carbó M, Eberl L
Environ Microbiol Rep 2020 Apr;12(2):241-249
PubMed ID: 32090500