Burkholderia cenocepacia J2315, BCAM0240 (cciR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAM0240
NCBI Locus TagQU43_RS55625
Name
cciR
Replicon chromosome 2
Genomic location 297531 - 298319 (- strand)

Cross-References

RefSeq YP_002232873.1
GI 206562110
Entrez 6930414
GI 206562110
NCBI Locus Tag QU43_RS55625
NCBI Old Locus Tag BCAM0240
RefSeq YP_002232873.1
UniProtKB Acc B4EI53
UniProtKB ID B4EI53_BURCJ

Product

Feature Type CDS
Coding Frame 1
Product Name
N-acylhomoserine lactone dependent regulatory protein
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) 9.78
Kyte-Doolittle Hydrophobicity Value -0.097
Molecular Weight (kDa) 28667.6
Isoelectric Point (pI) 10.03

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 195 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG003718 (1367 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAM0240
Search term: cciR

Human Homologs

References

Reciprocal regulation by the CepIR and CciIR quorum sensing systems in Burkholderia cenocepacia.
O'Grady EP, Viteri DF, Malott RJ, Sokol PA
BMC Genomics 2009 Sep 17;10:441
PubMed ID: 19761612
Characterization of the cciIR quorum-sensing system in Burkholderia cenocepacia.
Malott RJ, Baldwin A, Mahenthiralingam E, Sokol PA
Infect Immun 2005 Aug;73(8):4982-92
PubMed ID: 16041013