Burkholderia cenocepacia J2315, BCAM0184 (bclB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAM0184
NCBI Locus TagQU43_RS55335
Name
bclB
Replicon chromosome 2
Genomic location 214786 - 215520 (- strand)

Cross-References

RefSeq WP_006490839.1
GI 206562054
Entrez 6927980
GI 206562054
INSDC CAR54042.1
NCBI Locus Tag QU43_RS55335
NCBI Old Locus Tag BCAM0184
RefSeq WP_006490839.1,GeneID
UniParc UPI00017B9D2E
UniProtKB Acc B4EH85
UniProtKB ID B4EH85_BURCJ
UniRef100 UniRef100_B4EH85
UniRef50 UniRef50_Q0B5B6
UniRef90 UniRef90_Q0B5B6

Product

Feature Type CDS
Coding Frame 1
Product Name
BclB
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) -5.80
Kyte-Doolittle Hydrophobicity Value -0.064
Molecular Weight (kDa) 25560.6
Isoelectric Point (pI) 4.52

Subcellular localization

Individual Mappings
Localization Confidence PMID
Outer Membrane Class 3
Outer Membrane Class 1
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 6 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG004521 (98 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAM0184
Search term: bclB
Search term: BclB

Human Homologs

References

Identification of functions linking quorum sensing with biofilm formation in Burkholderia cenocepacia H111.
Inhülsen S, Aguilar C, Schmid N, Suppiger A, Riedel K, Eberl L
Microbiologyopen 2012 Jun;1(2):225-42
PubMed ID: 22950027