Burkholderia cenocepacia J2315, BCAL3486 (ecfM)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAL3486
NCBI Locus TagQU43_RS54160
Name
ecfM
Replicon chromosome 1
Genomic location 3823432 - 3824313 (- strand)

Cross-References

RefSeq WP_006487324.1
GI 206561823
Entrez 6933239
GI 206561823
INSDC CAR53809.1
NCBI Locus Tag QU43_RS54160
NCBI Old Locus Tag BCAL3486
RefSeq WP_006487324.1,GeneID
UniParc UPI00017B99D3
UniProtKB Acc B4E6L6
UniProtKB ID B4E6L6_BURCJ
UniRef100 UniRef100_A0A0D1DGY3
UniRef50 UniRef50_Q92XC9
UniRef90 UniRef90_A0K2P6

Product

Feature Type CDS
Coding Frame 1
Product Name
RNA polymerase sigma factor SigJ
Product Name Confidence: Class 1
Synonyms sigma factor 70 EcfM
Evidence for Translation
Charge (pH 7) -4.88
Kyte-Doolittle Hydrophobicity Value -0.200
Molecular Weight (kDa) 32741.1
Isoelectric Point (pI) 6.06

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 168 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000010 (703 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAL3486
Search term: ecfM

Human Homologs

References

Architecture of Burkholderia cepacia complex sigma70 gene family: evidence of alternative primary and clade-specific factors, and genomic instability.
Menard A, de Los Santos PE, Graindorge A, Cournoyer B
BMC Genomics 2007 Sep 4;8:308
PubMed ID: 17784948