Burkholderia cenocepacia J2315, BCAL3311 (bcnA)

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAL3311
NCBI Locus Tag	QU43_RS53255
Name	bcnA
Replicon	chromosome 1
Genomic location	3629192 - 3629752 (- strand)

Cross-References

RefSeq	WP_006482463.1
GI	206561649
Entrez	6933136
GI	206561649
INSDC	CAR53634.1
NCBI Locus Tag	QU43_RS53255
NCBI Old Locus Tag	BCAL3311
RefSeq	WP_006482463.1,GeneID
UniParc	UPI00017B9959
UniProtKB Acc	B4EE32
UniProtKB ID	B4EE32_BURCJ
UniRef100	UniRef100_U1XQX6
UniRef50	UniRef50_A0A060NUH4
UniRef90	UniRef90_A4JBN5

Product

Feature Type	CDS
Coding Frame	1
Product Name	BcnA Product Name Confidence: Class 1
Synonyms	hypothetical protein
Evidence for Translation
Charge (pH 7)	5.47
Kyte-Doolittle Hydrophobicity Value	-0.045
Molecular Weight (kDa)	19558.2
Isoelectric Point (pI)	10.02

Subcellular localization

Individual Mappings	Localization Confidence PMID Periplasmic Class 3 20472543 Extracellular Class 1 Western blot evidence used in manual assertion 28292982
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession	Header	Accession Date	Compound	Source	Resolution	Method	Percent Identity
5IXH	UNKNOWN FUNCTION	03/23/16	Crystal Structure of Burkholderia cenocepacia BcnA	BURKHOLDERIA CENOCEPACIA BC7	1.4	X-RAY DIFFRACTION	99.4

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 258 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG000589 (655 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAL3311 Search term: bcnA Search term: BcnA

Human Homologs

References

Antibiotic Capture by Bacterial Lipocalins Uncovers an Extracellular Mechanism of Intrinsic Antibiotic Resistance. El-Halfawy OM, Klett J, Ingram RJ, Loutet SA, Murphy ME, Martín-Santamaría S, Valvano MA mBio 2017 Mar 14;8(2) PubMed ID: 28292982