Burkholderia cenocepacia J2315, BCAL3133 (rmlC)

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAL3133
NCBI Locus Tag	QU43_RS52385
Name	rmlC
Replicon	chromosome 1
Genomic location	3424740 - 3425291 (- strand)

Cross-References

RefSeq	WP_006485116.1
GI	206561477
Entrez	6934048
GI	206561477
INSDC	CAR53456.1
NCBI Locus Tag	QU43_RS52385
NCBI Old Locus Tag	BCAL3133
RefSeq	WP_006485116.1,GeneID
UniParc	UPI00017B9994
UniProtKB Acc	B4ECS4
UniProtKB ID	B4ECS4_BURCJ
UniRef100	UniRef100_B4ECS4
UniRef50	UniRef50_Q2S4Z8
UniRef90	UniRef90_B4ECS4

Product

Feature Type	CDS
Coding Frame	1
Product Name	dTDP-4-keto-6-deoxy-D-glucose 3,5-epimerase Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7)	-7.56
Kyte-Doolittle Hydrophobicity Value	-0.210
Molecular Weight (kDa)	20715.3
Isoelectric Point (pI)	4.91

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 476 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG000732 (654 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAL3133 Search term: rmlC Search term: dTDP-4-keto-6-deoxy-D-glucose 3,5-epimerase

Human Homologs

References

A new route to dTDP-6-deoxy-l-talose and dTDP-L-rhamnose: dTDP-L-rhamnose 4-epimerase in Burkholderia thailandensis. Yoo HG, Kwon SY, Karki S, Kwon HJ Bioorg Med Chem Lett 2011 Jul 1;21(13):3914-7 PubMed ID: 21640586