Burkholderia cenocepacia J2315, BCAL3124 (wbxD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAL3124
NCBI Locus TagQU43_RS52350
Name
wbxD
Replicon chromosome 1
Genomic location 3414875 - 3416842 (- strand)
CommentBelongs to the O antigen biosynthesis gene cluster

Cross-References

RefSeq WP_006493012.1
GI 206561470
Entrez 6934245
GI 206561470
INSDC CAR53448.1
NCBI Locus Tag QU43_RS52350
NCBI Old Locus Tag BCAL3124
RefSeq WP_006493012.1,GeneID
UniParc UPI00017B998E
UniProtKB Acc B4ECE5
UniProtKB ID B4ECE5_BURCJ
UniRef100 UniRef100_B4ECE5
UniRef50 UniRef50_B4ECE5
UniRef90 UniRef90_B4ECE5

Product

Feature Type CDS
Coding Frame 1
Product Name
glycosyltransferase
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) -14.70
Kyte-Doolittle Hydrophobicity Value -0.207
Molecular Weight (kDa) 73024.7
Isoelectric Point (pI) 5.61

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 563 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000137 (1280 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAL3124
Search term: wbxD

References

Reconstitution of O-specific lipopolysaccharide expression in Burkholderia cenocepacia strain J2315, which is associated with transmissible infections in patients with cystic fibrosis.
Ortega X, Hunt TA, Loutet S, Vinion-Dubiel AD, Datta A, Choudhury B, Goldberg JB, Carlson R, Valvano MA
J Bacteriol 2005 Feb;187(4):1324-33
PubMed ID: 15687196