Burkholderia cenocepacia J2315, BCAL3123 (wbxC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAL3123
NCBI Locus TagQU43_RS52345
Name
wbxC
Replicon chromosome 1
Genomic location 3414162 - 3414830 (+ strand)
CommentBelongs to the O antigen biosynthesis gene cluster

Cross-References

RefSeq WP_012492905.1
GI 206561469
Entrez 6934239
GI 206561469
INSDC CAR53447.1
NCBI Locus Tag QU43_RS52345
NCBI Old Locus Tag BCAL3123
RefSeq WP_012492905.1,GeneID
UniParc UPI00017B998D
UniProtKB Acc B4ECE4
UniProtKB ID B4ECE4_BURCJ
UniRef100 UniRef100_B4ECE4
UniRef50 UniRef50_B4ECE4
UniRef90 UniRef90_B4ECE4

Product

Feature Type CDS
Coding Frame 1
Product Name
acetyltransferase
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) -0.02
Kyte-Doolittle Hydrophobicity Value 0.194
Molecular Weight (kDa) 23371.5
Isoelectric Point (pI) 6.99

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 428 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG006202 (122 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAL3123
Search term: wbxC
Search term: acetyltransferase

Human Homologs

References

Reconstitution of O-specific lipopolysaccharide expression in Burkholderia cenocepacia strain J2315, which is associated with transmissible infections in patients with cystic fibrosis.
Ortega X, Hunt TA, Loutet S, Vinion-Dubiel AD, Datta A, Choudhury B, Goldberg JB, Carlson R, Valvano MA
J Bacteriol 2005 Feb;187(4):1324-33
PubMed ID: 15687196