Burkholderia cenocepacia J2315, BCAL3120 (wbiH)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAL3120
NCBI Locus TagQU43_RS52330
Name
wbiH
Replicon chromosome 1
Genomic location 3411022 - 3412038 (- strand)
CommentBelongs to the O antigen biosynthesis gene cluster

Cross-References

RefSeq WP_012492902.1
GI 206561466
Entrez 6934242
GI 206561466
INSDC CAR53444.1
NCBI Locus Tag QU43_RS52330
NCBI Old Locus Tag BCAL3120
RefSeq WP_012492902.1,GeneID
UniParc UPI00017B9957
UniProtKB Acc B4ECE1
UniProtKB ID B4ECE1_BURCJ
UniRef100 UniRef100_B4ECE1
UniRef50 UniRef50_Q39IY4
UniRef90 UniRef90_B4ECE1

Product

Feature Type CDS
Coding Frame 1
Product Name
UDP-N-acetylglucosamine-1-P transferase
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) 9.64
Kyte-Doolittle Hydrophobicity Value 0.646
Molecular Weight (kDa) 36916.1
Isoelectric Point (pI) 10.39

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 468 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000741 (647 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAL3120
Search term: wbiH

Human Homologs

References

Reconstitution of O-specific lipopolysaccharide expression in Burkholderia cenocepacia strain J2315, which is associated with transmissible infections in patients with cystic fibrosis.
Ortega X, Hunt TA, Loutet S, Vinion-Dubiel AD, Datta A, Choudhury B, Goldberg JB, Carlson R, Valvano MA
J Bacteriol 2005 Feb;187(4):1324-33
PubMed ID: 15687196