Burkholderia cenocepacia J2315, BCAL3117 (galE)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAL3117
NCBI Locus TagQU43_RS52315
Name
galE
Replicon chromosome 1
Genomic location 3406891 - 3407913 (+ strand)
CommentBelongs to the O antigen biosynthesis gene cluster

Cross-References

RefSeq WP_006485111.1
GI 206561463
Entrez 6934244
GI 206561463
INSDC CAR53441.1
NCBI Locus Tag QU43_RS52315
NCBI Old Locus Tag BCAL3117
RefSeq WP_006485111.1,GeneID
UniParc UPI00017B9954
UniProtKB Acc B4ECD8
UniProtKB ID B4ECD8_BURCJ
UniRef100 UniRef100_B4ECD8
UniRef50 UniRef50_P24325
UniRef90 UniRef90_A9AF83

Product

Feature Type CDS
Coding Frame 1
Product Name
UDP-glucose epimerase
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) -5.16
Kyte-Doolittle Hydrophobicity Value -0.070
Molecular Weight (kDa) 36862.6
Isoelectric Point (pI) 5.88

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 642 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000745 (653 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAL3117
Search term: galE

Human Homologs

Ensembl 97, assembly GRCh38.p12
UDP-galactose-4-epimerase [Source:HGNC Symbol;Acc:HGNC:4116]
E-value: 4.9e-116
Percent Identity: 57.4

Human Homologs

Ensembl 97, assembly GRCh38.p12
UDP-galactose-4-epimerase [Source:HGNC Symbol;Acc:HGNC:4116]
E-value: 4.9e-116
Percent Identity: 57.4

References

Reconstitution of O-specific lipopolysaccharide expression in Burkholderia cenocepacia strain J2315, which is associated with transmissible infections in patients with cystic fibrosis.
Ortega X, Hunt TA, Loutet S, Vinion-Dubiel AD, Datta A, Choudhury B, Goldberg JB, Carlson R, Valvano MA
J Bacteriol 2005 Feb;187(4):1324-33
PubMed ID: 15687196