Burkholderia cenocepacia J2315, BCAL3116 (wbxB)

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAL3116
NCBI Locus Tag	QU43_RS52310
Name	wbxB
Replicon	chromosome 1
Genomic location	3405739 - 3406875 (+ strand)
Comment	Belongs to the O antigen biosynthesis gene cluster

Cross-References

RefSeq	WP_006485113.1
GI	206561462
Entrez	6934243
GI	206561462
INSDC	CAR53440.1
NCBI Locus Tag	QU43_RS52310
NCBI Old Locus Tag	BCAL3116
RefSeq	WP_006485113.1,GeneID
UniParc	UPI00017B9953
UniProtKB Acc	B4ECD7
UniProtKB ID	B4ECD7_BURCJ
UniRef100	UniRef100_B4ECD7
UniRef50	UniRef50_A3NYE0
UniRef90	UniRef90_B4ECD7

Product

Feature Type	CDS
Coding Frame	1
Product Name	glycosyltransferase Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7)	6.26
Kyte-Doolittle Hydrophobicity Value	0.006
Molecular Weight (kDa)	41766.7
Isoelectric Point (pI)	8.68

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 549 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG000746 (652 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAL3116 Search term: wbxB Search term: glycosyltransferase

Human Homologs

References

Reconstitution of O-specific lipopolysaccharide expression in Burkholderia cenocepacia strain J2315, which is associated with transmissible infections in patients with cystic fibrosis. Ortega X, Hunt TA, Loutet S, Vinion-Dubiel AD, Datta A, Choudhury B, Goldberg JB, Carlson R, Valvano MA J Bacteriol 2005 Feb;187(4):1324-33 PubMed ID: 15687196