Burkholderia cenocepacia J2315, BCAL3115 (wbxA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAL3115
NCBI Locus TagQU43_RS52305
Name
wbxA
Replicon chromosome 1
Genomic location 3404899 - 3405687 (+ strand)
CommentBelongs to the O antigen biosynthesis gene cluster

Cross-References

RefSeq YP_002232226.1
GI 206561461
Entrez 6934263
GI 206561461
NCBI Locus Tag QU43_RS52305
NCBI Old Locus Tag BCAL3115
RefSeq YP_002232226.1
UniProtKB Acc B4ECD6
UniProtKB ID B4ECD6_BURCJ

Product

Feature Type CDS
Coding Frame 1
Product Name
glycosyltransferase
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) 12.37
Kyte-Doolittle Hydrophobicity Value -0.096
Molecular Weight (kDa) 29251.6
Isoelectric Point (pI) 10.36

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 184 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000747 (653 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAL3115
Search term: wbxA

Human Homologs

References

Reconstitution of O-specific lipopolysaccharide expression in Burkholderia cenocepacia strain J2315, which is associated with transmissible infections in patients with cystic fibrosis.
Ortega X, Hunt TA, Loutet S, Vinion-Dubiel AD, Datta A, Choudhury B, Goldberg JB, Carlson R, Valvano MA
J Bacteriol 2005 Feb;187(4):1324-33
PubMed ID: 15687196