Burkholderia cenocepacia J2315, BCAL3112 (waaC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAL3112
NCBI Locus TagQU43_RS52290
Name
waaC
Replicon chromosome 1
Genomic location 3400803 - 3401798 (- strand)

Cross-References

RefSeq WP_006485129.1
GI 206561458
Entrez 6934248
GI 206561458
INSDC CAR53436.1
NCBI Locus Tag QU43_RS52290
NCBI Old Locus Tag BCAL3112
RefSeq WP_006485129.1,GeneID
UniParc UPI000170D2E3
UniProtKB Acc B4ECD3
UniProtKB ID B4ECD3_BURCJ
UniRef100 UniRef100_B1JX23
UniRef50 UniRef50_Q2SYG3
UniRef90 UniRef90_B9BAY0

Product

Feature Type CDS
Coding Frame 1
Product Name
heptosyltransferase I WaaC
Product Name Confidence: Class 1
Synonyms heptosyltransferase I
Evidence for Translation
Charge (pH 7) 11.17
Kyte-Doolittle Hydrophobicity Value 0.089
Molecular Weight (kDa) 36104.4
Isoelectric Point (pI) 10.51

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Unknown Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 232 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000750 (654 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAL3112
Search term: waaC

References

Reconstitution of O-specific lipopolysaccharide expression in Burkholderia cenocepacia strain J2315, which is associated with transmissible infections in patients with cystic fibrosis.
Ortega X, Hunt TA, Loutet S, Vinion-Dubiel AD, Datta A, Choudhury B, Goldberg JB, Carlson R, Valvano MA.
J Bacteriol. 2005 Feb;187(4):1324-33.
PubMed ID: 15687196
Biosynthesis and structure of the Burkholderia cenocepacia K56-2 lipopolysaccharide core oligosaccharide: truncation of the core oligosaccharide leads to increased binding and sensitivity to polymyxin B.
Ortega X, Silipo A, Saldias MS, Bates CC, Molinaro A, Valvano MA.
J Biol Chem. 2009 Aug 7;284(32):21738-5Epub 2009 Jun 12.
PubMed ID: 19525227