Burkholderia cenocepacia J2315, BCAL2946 (udg)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAL2946
NCBI Locus TagQU43_RS51375
Name
udg
Replicon chromosome 1
Genomic location 3224205 - 3225605 (- strand)

Cross-References

RefSeq WP_006486856.1
GI 206561281
Entrez 6933725
GI 206561281
INSDC CAR53247.1
NCBI Locus Tag QU43_RS51375
NCBI Old Locus Tag BCAL2946
RefSeq WP_006486856.1,GeneID
UniParc UPI00017B9733
UniProtKB Acc B4EB36
UniProtKB ID B4EB36_BURCJ
UniRef100 UniRef100_G7HIB2
UniRef50 UniRef50_Q72AT3
UniRef90 UniRef90_B9BSF4

Product

Feature Type CDS
Coding Frame 1
Product Name
putative UDP-glucose dehydrogenase
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) -10.90
Kyte-Doolittle Hydrophobicity Value -0.117
Molecular Weight (kDa) 50895.3
Isoelectric Point (pI) 5.16

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown (This protein may have multiple localization sites) Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 589 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000893 (1284 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAL2946
Search term: udg

References

A complete lipopolysaccharide inner core oligosaccharide is required for resistance of Burkholderia cenocepacia to antimicrobial peptides and bacterial survival in vivo.
Loutet SA, Flannagan RS, Kooi C, Sokol PA, Valvano MA
J Bacteriol 2006 Mar;188(6):2073-80
PubMed ID: 16513737
Contributions of two UDP-glucose dehydrogenases to viability and polymyxin B resistance of Burkholderia cenocepacia.
Loutet SA, Bartholdson SJ, Govan JRW, Campopiano DJ, Valvano MA
Microbiology 2009 Jun;155(Pt 6):2029-2039
PubMed ID: 19383677