Strain |
Burkholderia cenocepacia J2315
GCF_000009485.1|latest |
Locus Tag |
BCAL2829
|
NCBI Locus Tag | QU43_RS50760 |
Name |
htrA
|
Replicon | chromosome 1 |
Genomic location | 3106541 - 3108025 (- strand) |
RefSeq | WP_006490099.1 |
GI | 206561166 |
Entrez | 6932826 |
GI | 206561166 |
INSDC | CAR53129.1 |
NCBI Locus Tag | QU43_RS50760 |
NCBI Old Locus Tag | BCAL2829 |
RefSeq | WP_006490099.1,GeneID |
UniParc | UPI00017B9987 |
UniProtKB Acc | B4EA13 |
UniProtKB ID | B4EA13_BURCJ |
UniRef100 | UniRef100_B4EA13 |
UniRef50 | UniRef50_Q1LH84 |
UniRef90 | UniRef90_B1YVV2 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
HtrA protease
|
Synonyms |
subfamily S1B serine peptidase |
Evidence for Translation | |
Charge (pH 7) | 2.20 |
Kyte-Doolittle Hydrophobicity Value | -0.022 |
Molecular Weight (kDa) | 50966.4 |
Isoelectric Point (pI) | 8.66 |
Individual Mappings | |
Additional evidence for subcellular localization |
Source 1 | |
Database | BGD |
Category | Protease |
Evidence |
ECO:0000315
mutant phenotype evidence used in manual assertion
|
Host Organism | Rattus norvegicus |
Notes | htrA mutant attenuated for virulence in agar bead model of chronic lung infection |
Reference | 17220310 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 614 genera
|
Burkholderia Ortholog Group |
BG002475 (654 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: BCAL2829
Search term: htrA
Search term: HtrA protease
|
Ensembl
97, assembly
GRCh38.p12
|
HtrA serine peptidase 3 [Source:HGNC Symbol;Acc:HGNC:30406]
E-value:
1.5e-36
Percent Identity:
37.1
|
Burkholderia cenocepacia requires a periplasmic HtrA protease for growth under thermal and osmotic stress and for survival in vivo.
Flannagan RS, Aubert D, Kooi C, Sokol PA, Valvano MA
Infect Immun 2007 Apr;75(4):1679-89
PubMed ID: 17220310
|
Burkholderia cenocepacia requires a periplasmic HtrA protease for growth under thermal and osmotic stress and for survival in vivo.
Flannagan RS, Aubert D, Kooi C, Sokol PA, Valvano MA
Infect Immun 2007 Apr;75(4):1679-89
PubMed ID: 17220310
|